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| China Open | ||
| Surface: Hard | Date: Sep. 30 - Oct. 8 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Bye |
| Toray Pan Pacific Open Tennis Tournament | ||
| Surface: Hard | Date: Sep. 25 - Oct. 1 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Harriet Dart | Win | 6-3, 7-6 (7-4) |
| Second Round | Kayla Day | Win | 6-3, 6-3 |
| Quarterfinals | Iga Swiatek | Win | 6-2, 2-6, 6-4 |
| Semifinals | Anastasia Pavlyuchenkova |
| Guadalajara Open Akron | ||
| Surface: Hard | Date: Sep. 17 - Sep. 24 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Eugenie Bouchard | Win | 6-2, 6-7 (4-7), 6-4 |
| Third Round | Victoria Azarenka | Loss | 2-6, 1-6 |
| San Diego Open | ||
| Surface: Hard | Date: Sep. 11 - Sep. 16 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Sofia Kenin | Loss | 4-6, 4-6 |
| US Open | ||
| Surface: Hard | Date: Aug. 28 - Sep. 9 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Bernarda Pera | Loss | 5-7, 4-6 |
| Tennis in the Land | ||
| Surface: Hard | Date: Aug. 20 - Aug. 26 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Nadia Podoroska | Win | 3-6, 6-2, 6-1 |
| Second Round | Sara Sorribes Tormo | Loss | 4-6, 1-6 |
| Western & Southern Open | ||
| Surface: Hard | Date: Aug. 14 - Aug. 20 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Venus Williams | Loss | 4-6, 5-7 |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 3 - Jul. 15 | Seed: 12 |
| Round | Opponent | W / L | Result |
| First Round | Kaia Kanepi | Win | |
| Second Round | Marketa Vondrousova | Loss |
| Bett1 Open | ||
| Surface: Grass | Date: Jun. 19 - Jun. 25 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Qinwen Zheng | Win | |
| Second Round | Aryna Sabalenka | Win | |
| Quarterfinals | Ekaterina Alexandrova | Loss |
| Libema Open | ||
| Surface: Grass | Date: Jun. 12 - Jun. 18 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Alison Riske-Amritraj | Win | |
| Second Round | Carol Zhao | Win | |
| Quarterfinals | Celine Naef | Win | |
| Semifinals | Viktoria Hruncakova | Win | |
| Final | Ekaterina Alexandrova | Loss |
| French Open | ||
| Surface: Red Clay | Date: May 28 - Jun. 10 | Seed: 11 |
| Round | Opponent | W / L | Result |
| First Round | Anna Karolina Schmiedlova | Loss |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 9 - May 21 | Seed: 11 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Nuria Parrizas Diaz | Win | |
| Third Round | Anastasia Potapova | Win | |
| Fourth Round | Marie Bouzkova | Win | |
| Quarterfinals | Qinwen Zheng | Win | |
| Semifinals | Anhelina Kalinina | Loss |
| Mutua Madrid Open | ||
| Surface: Hard | Date: Apr. 25 - May 6 | Seed: 12 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Nuria Parrizas Diaz | Win | |
| Third Round | Anastasia Potapova | Win | |
| Fourth Round | Daria Kasatkina | Win | |
| Quarterfinals | Jessica Pegula | Win | |
| Semifinals | Iga Swiatek | Loss |
| Porsche Tennis Grand Prix | ||
| Surface: Clay | Date: Apr. 17 - Apr. 23 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Coco Gauff | Loss |
| Credit One Charleston Open | ||
| Surface: Green Clay | Date: Apr. 3 - Apr. 9 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Diana Shnaider | Loss |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 21 - Apr. 1 | Seed: 11 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Marketa Vondrousova | Loss |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 8 - Mar. 19 | Seed: 11 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Anna Blinkova | Win | |
| Third Round | Karolina Pliskova | Loss |
| Dubai Duty Free Tennis Championships | ||
| Surface: Hard | Date: Feb. 19 - Feb. 25 | Seed: 10 |
| Round | Opponent | W / L | Result |
| First Round | Anhelina Kalinina | Loss |
| Qatar Total Energies Open | ||
| Surface: Hard | Date: Feb. 13 - Feb. 18 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Barbora Krejcikova | Win | |
| Second Round | Sofia Kenin | Win | |
| Quarterfinals | Coco Gauff | Win | |
| Semifinals | Iga Swiatek | Loss |
| Mubadala Abu Dhabi Open | ||
| Surface: Hard | Date: Feb. 6 - Feb. 12 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Elise Mertens | Win | |
| Quarterfinals | Liudmila Samsonova | Loss |
| Australian Open | ||
| Surface: Hard | Date: Jan. 15 - Jan. 28 | Seed: 9 |
| Round | Opponent | W / L | Result |
| First Round | Maryna Zanevska | Win | |
| Second Round | Katie Volynets | Loss |
| Adelaide International 2 | ||
| Surface: Hard | Date: Jan. 9 - Jan. 14 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Victoria Azarenka | Win | |
| Second Round | Ekaterina Alexandrova | Win | |
| Quarterfinals | Danielle Collins | Win | |
| Semifinals | Belinda Bencic | Loss |
| Adelaide International 1 | ||
| Surface: Hard | Date: Dec. 31 - Jan. 8 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Amanda Anisimova | Win | |
| Second Round | Bianca Andreescu | Win | |
| Quarterfinals | Irina-Camelia Begu | Loss |
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