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| Guadalajara Open Akron | ||
| Surface: Hard | Date: Sep. 17 - Sep. 24 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Marta Kostyuk | Win | 6-2, 6-3 |
| Third Round | Sofia Kenin | Loss | 4-6, 5-7 |
| San Diego Open | ||
| Surface: Hard | Date: Sep. 11 - Sep. 16 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Ekaterina Alexandrova | Win | 7-6 (7-3), 6-7 (6-8), 7-5 |
| Second Round | Danielle Collins | Loss | 6-2, 3-6, 4-6 |
| US Open | ||
| Surface: Hard | Date: Aug. 28 - Sep. 9 | Seed: 20 |
| Round | Opponent | W / L | Result |
| First Round | Jasmine Paolini | Win | 6-2, 4-6, 6-1 |
| Second Round | Elina Avanesyan | Win | 6-3, 5-7, 7-5 |
| Third Round | Bernarda Pera | Win | 4-6, 6-3, 6-3 |
| Fourth Round | Iga Swiatek | Win | 3-6, 6-3, 6-1 |
| Quarterfinals | Coco Gauff | Loss | 0-6, 2-6 |
| Western & Southern Open | ||
| Surface: Hard | Date: Aug. 14 - Aug. 20 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Karolina Pliskova | Win | 1-6, 6-3, 6-4 |
| Second Round | Elena Rybakina | Loss | 7-6 (8-6), 2-6, 4-6 |
| Omnium National Bank presented by Rogers | ||
| Surface: Hard | Date: Aug. 7 - Aug. 13 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Jennifer Brady | Loss | 6-7 (7-9), 6-0, 6-7 (8-10) |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 3 - Jul. 15 | Seed: 17 |
| Round | Opponent | W / L | Result |
| First Round | Greet Minnen | Win | |
| Second Round | Sorana Cirstea | Loss |
| Rothesay International Eastbourne | ||
| Surface: Grass | Date: Jun. 25 - Jul. 1 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Barbora Strycova | Win | |
| Second Round | Harriet Dart | Win | |
| Quarterfinals | Camila Giorgi | Loss |
| Rothesay Classic Birmingham | ||
| Surface: Grass | Date: Jun. 19 - Jun. 25 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Linda Noskova | Win | |
| Second Round | Venus Williams | Win | |
| Quarterfinals | Magdalena Frech | Win | |
| Semifinals | Anastasia Potapova | Win | |
| Final | Barbora Krejcikova | Win |
| French Open | ||
| Surface: Red Clay | Date: May 28 - Jun. 10 | Seed: 17 |
| Round | Opponent | W / L | Result |
| First Round | Tereza Martincova | Win | |
| Second Round | Peyton Stearns | Loss |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 9 - May 21 | Seed: 20 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Sorana Cirstea | Win | |
| Third Round | Barbora Krejcikova | Win | |
| Fourth Round | Daria Kasatkina | Win | |
| Quarterfinals | Paula Badosa | Win | |
| Semifinals | Elena Rybakina | Loss |
| Mutua Madrid Open | ||
| Surface: Hard | Date: Apr. 25 - May 6 | Seed: 19 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Linda Fruhvirtova | Win | |
| Third Round | Liudmila Samsonova | Loss |
| Porsche Tennis Grand Prix | ||
| Surface: Clay | Date: Apr. 17 - Apr. 23 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Emma Raducanu | Win | |
| Second Round | Ons Jabeur | Loss |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 21 - Apr. 1 | Seed: 24 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Mirjam Bjorklund | Win | |
| Third Round | Beatriz Haddad Maia | Win | |
| Fourth Round | Martina Trevisan | Loss |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 8 - Mar. 19 | Seed: 24 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Aliaksandra Sasnovich | Win | |
| Third Round | Petra Kvitova | Loss |
| Dubai Duty Free Tennis Championships | ||
| Surface: Hard | Date: Feb. 19 - Feb. 25 | Seed: 13 |
| Round | Opponent | W / L | Result |
| First Round | Katarina Zavatska | Win | |
| Second Round | Linda Fruhvirtova | Win | |
| Third Round | Aryna Sabalenka | Loss |
| Qatar Total Energies Open | ||
| Surface: Hard | Date: Feb. 13 - Feb. 18 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Madison Keys | Win | |
| Second Round | Jessica Pegula | Loss |
| Mubadala Abu Dhabi Open | ||
| Surface: Hard | Date: Feb. 6 - Feb. 12 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Danielle Collins | Win | |
| Second Round | Qinwen Zheng | Loss |
| Australian Open | ||
| Surface: Hard | Date: Jan. 15 - Jan. 28 | Seed: 17 |
| Round | Opponent | W / L | Result |
| First Round | Dayana Yastremska | Win | |
| Second Round | Anna Bondar | Win | |
| Third Round | Kateryna Baindl | Win | |
| Fourth Round | Coco Gauff | Win | |
| Quarterfinals | Elena Rybakina | Loss |
| Adelaide International 2 | ||
| Surface: Hard | Date: Jan. 9 - Jan. 14 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Anna Kalinskaya | Loss |
| Adelaide International 1 | ||
| Surface: Hard | Date: Dec. 31 - Jan. 8 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Karolina Pliskova | Win | |
| Second Round | Irina-Camelia Begu | Loss |
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