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| China Open | ||
| Surface: Hard | Date: Sep. 28 - Oct. 6 | Seed: 13 |
| Round | Opponent | W / L | Result |
| First Round | Magda Linette | Win | 7-5, 6-3 |
| Second Round | Saisai Zheng | Loss | 3-6, 1-6 |
| Dongfeng Motor Wuhan Open | ||
| Surface: Hard | Date: Sep. 22 - Sep. 28 | Seed: 10 |
| Round | Opponent | W / L | Result |
| First Round | Shuai Zhang | Win | 7-5, 6-4 |
| Second Round | Yafan Wang | Win | 6-2, 3-6, 6-1 |
| Third Round | Petra Kvitova | Loss | 3-6, 3-6 |
| Toray Pan Pacific Open | ||
| Surface: Decoturf | Date: Sep. 16 - Sep. 22 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Camila Giorgi | Loss | 0-6, 3-6 |
| US Open | ||
| Surface: Hard | Date: Aug. 26 - Sep. 8 | Seed: 11 |
| Round | Opponent | W / L | Result |
| First Round | Anna Kalinskaya | Loss | 3-6, 4-6 |
| Western & Southern Womens Open | ||
| Surface: Hard | Date: Aug. 11 - Aug. 18 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Yulia Putintseva | Win | 2-6, 6-4, 6-3 |
| Third Round | Svetlana Kuznetsova | Loss | 1-6, 2-6 |
| Rogers Cup presented by National Bank | ||
| Surface: Hard | Date: Aug. 5 - Aug. 11 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Marie Bouzkova | Loss | 2-6, 5-7 |
| Citi Open | ||
| Surface: Hard | Date: Jul. 29 - Aug. 4 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Rebecca Peterson | Loss | 2-6, 5-7 |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 1 - Jul. 14 | Seed: 9 |
| Round | Opponent | W / L | Result |
| First Round | Timea Bacsinszky | Win | 6-2, 6-4 |
| Second Round | Yafan Wang | Win | 6-0, 6-2 |
| Third Round | Johanna Konta | Loss | 6-3, 4-6, 1-6 |
| Nature Valley International | ||
| Surface: Grass | Date: Jun. 23 - Jun. 29 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Jelena Ostapenko | Loss | 6-1, 0-6, 3-6 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 26 - Jun. 9 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Misaki Doi | Win | 6-3, 7-6 (7-4) |
| Second Round | Sara Sorribes Tormo | Win | 6-1, 7-6 (7-3) |
| Third Round | Polona Hercog | Win | 6-3, 5-7, 6-4 |
| Fourth Round | Garbine Muguruza | Win | 6-4, 6-3 |
| Quarterfinals | Johanna Konta | Loss | 1-6, 4-6 |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 12 - May 19 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Johanna Konta | Loss | 7-6 (7-3), 4-6, 1-6 |
| Mutua Madrid Open | ||
| Surface: Red Clay | Date: May 4 - May 12 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Polona Hercog | Win | 6-2, 7-6 (7-4) |
| Second Round | Victoria Azarenka | Win | 6-4, 2-6, 6-2 |
| Third Round | Saisai Zheng | Win | 3-6, 6-3, 6-2 |
| Quarterfinals | Petra Martic | Win | 6-4, 6-3 |
| Semifinals | Kiki Bertens | Loss | 2-6, 5-7 |
| Volvo Car Open | ||
| Surface: Green Clay | Date: Apr. 1 - Apr. 7 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Sara Sorribes Tormo | Win | 7-6 (7-4), 7-6 (7-4) |
| Third Round | Ajla Tomljanovic | Win | 4-6, 6-4, 6-4 |
| Quarterfinals | Madison Keys | Loss | 6-7 (6-8), 6-4, 2-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 19 - Mar. 31 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Ons Jabeur | Win | 6-2, 6-3 |
| Third Round | Tatjana Maria | Loss | 3-6, 2-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 6 - Mar. 17 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Stefanie Voegele | Loss | 3-6, 0-6 |
| Abierto Mexicano TELCEL presentado por HSBC | ||
| Surface: Hard | Date: Feb. 25 - Mar. 3 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Pauline Parmentier | Win | 6-2, 6-2 |
| Second Round | Beatriz Haddad Maia | Loss | 3-6, 3-6 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 14 - Jan. 27 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Taylor Townsend | Win | 6-4, 6-2 |
| Second Round | Timea Babos | Win | 6-3, 6-1 |
| Third Round | Petra Martic | Win | 7-6 (8-6), 7-6 (7-5) |
| Fourth Round | Anastasia Pavlyuchenkova | Loss | 7-6 (7-3), 3-6, 3-6 |
| Sydney International | ||
| Surface: Hard | Date: Jan. 6 - Jan. 12 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Ekaterina Alexandrova | Win | 0-6, 7-6 (7-3), 7-6 (7-3) |
| Second Round | Yulia Putintseva | Loss | 6-3, 6-7 (4-7), 0-6 |
| Brisbane International presented by Suncorp | ||
| Surface: Hard | Date: Dec. 31 - Jan. 6 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Johanna Konta | Loss | 4-6, 3-6 |
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