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| BNP Paribas WTA Finals Singapore | ||
| Surface: Hard | Date: Oct. 21 - Oct. 28 | Seed: 5 |
| Round | Opponent | W / L | Result |
| Round Robin | Naomi Osaka | Win | 7-5, 4-6, 6-1 7-6 (7-4), 2-6, 6-3 6-3, 6-3 |
| Round Robin | Kiki Bertens | Win | 7-5, 4-6, 6-1 7-6 (7-4), 2-6, 6-3 6-3, 6-3 |
| Round Robin | Angelique Kerber | Win | 7-5, 4-6, 6-1 7-6 (7-4), 2-6, 6-3 6-3, 6-3 |
| Semifinals | Karolina Pliskova | Win | 0-6, 6-4, 6-1 |
| Final | Elina Svitolina | Loss | 6-3, 2-6, 2-6 |
| VTB Kremlin Cup | ||
| Surface: Hard | Date: Oct. 15 - Oct. 21 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Ons Jabeur | Loss | 3-6, 2-6 |
| China Open | ||
| Surface: Hard | Date: Sep. 29 - Oct. 7 | Seed: 9 |
| Round | Opponent | W / L | Result |
| First Round | Anastasia Pavlyuchenkova | Win | 6-7 (8-10), 6-4, 6-4 |
| Second Round | Saisai Zheng | Win | 6-1, 6-3 |
| Third Round | Dominika Cibulkova | Loss | 6-4, 2-6, 3-6 |
| Dongfeng Motor Wuhan Open | ||
| Surface: Hard | Date: Sep. 23 - Sep. 29 | Seed: 9 |
| Round | Opponent | W / L | Result |
| First Round | Anett Kontaveit | Loss | 6-4, 5-7, 4-6 |
| Toray Pan Pacific Open | ||
| Surface: Hard | Date: Sep. 17 - Sep. 23 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Donna Vekic | Loss | 4-6, 4-6 |
| US Open | ||
| Surface: Hard | Date: Aug. 27 - Sep. 9 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Evgeniya Rodina | Win | 6-1, 7-5 |
| Second Round | Anhelina Kalinina | Win | 4-6, 7-5, 6-2 |
| Third Round | Victoria Azarenka | Win | 6-3, 6-4 |
| Fourth Round | Elise Mertens | Win | 6-3, 6-3 |
| Quarterfinals | Anastasija Sevastova | Loss | 2-6, 3-6 |
| Western & Southern Womens Open | ||
| Surface: Hard | Date: Aug. 12 - Aug. 19 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Tatjana Maria | Win | 6-3, 6-2 |
| Third Round | Elise Mertens | Loss | 6-7 (8-10), 2-6 |
| Coupe Rogers presentee par Banque Nationale | ||
| Surface: Hard | Date: Aug. 6 - Aug. 12 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Francoise Abanda | Win | 6-0, 6-2 |
| Third Round | Carla Suarez Navarro | Win | 6-2, 7-5 |
| Quarterfinals | Anastasija Sevastova | Win | 6-2, 6-2 |
| Semifinals | Elina Svitolina | Win | 6-3, 6-3 |
| Final | Simona Halep | Loss | 6-7 (6-8), 6-3, 4-6 |
| Citi Open | ||
| Surface: Hard | Date: Jul. 30 - Aug. 5 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bethanie Mattek-Sands | Win | 7-5, 6-4 |
| Second Round | Andrea Petkovic | Loss | 6-2, 4-6, 2-6 |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 2 - Jul. 15 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Donna Vekic | Loss | 1-6, 3-6 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 27 - Jun. 10 | Seed: 10 |
| Round | Opponent | W / L | Result |
| First Round | Arantxa Rus | Win | 6-2, 6-0 |
| Second Round | Magdalena Frech | Win | 6-2, 6-2 |
| Third Round | Camila Giorgi | Win | 4-6, 6-1, 8-6 |
| Fourth Round | Anett Kontaveit | Win | 6-2, 6-0 |
| Quarterfinals | Daria Kasatkina | Win | 6-3, 6-1 |
| Semifinals | Madison Keys | Win | 6-4, 6-4 |
| Final | Simona Halep | Loss | 6-3, 4-6, 1-6 |
| Nurnberger Versicherungscup | ||
| Surface: Clay | Date: May 20 - May 26 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Yulia Putintseva | Loss | 7-5, 4-6, 6-7 (3-7) |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 13 - May 20 | Seed: 9 |
| Round | Opponent | W / L | Result |
| First Round | Barbora Strycova | Win | 6-7 (4-7), 6-3, 6-1 |
| Second Round | Kaia Kanepi | Win | 6-0, 5-7, 6-4 |
| Third Round | Caroline Garcia | Loss | 1-6, 6-7 (7-9) |
| Mutua Madrid Open | ||
| Surface: Red Clay | Date: May 5 - May 13 | Seed: 9 |
| Round | Opponent | W / L | Result |
| First Round | Silvia Soler-Espinosa | Win | 6-3, 6-2 |
| Second Round | Samantha Stosur | Win | 6-1, 6-3 |
| Third Round | Karolina Pliskova | Loss | 2-6, 3-6 |
| Porsche Tennis Grand Prix | ||
| Surface: Clay | Date: Apr. 23 - Apr. 29 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Coco Vandeweghe | Loss | 1-6, 0-6 |
| Volvo Car Open | ||
| Surface: Green Clay | Date: Apr. 2 - Apr. 8 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 20 - Apr. 1 | Seed: 13 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Ajla Tomljanovic | Win | 6-1, 6-3 |
| Third Round | Monica Niculescu | Win | 6-7 (1-7), 6-3, 4-0 Retired |
| Fourth Round | Garbine Muguruza | Win | 6-3, 6-4 |
| Quarterfinals | Angelique Kerber | Win | 6-1, 6-2 |
| Semifinals | Victoria Azarenka | Win | 3-6, 6-2, 6-1 |
| Final | Jelena Ostapenko | Win | 7-6 (7-5), 6-1 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 7 - Mar. 18 | Seed: 13 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Victoria Azarenka | Win | 6-1, 7-5 |
| Third Round | Daria Kasatkina | Loss | 4-6, 3-6 |
| Abierto Mexicano TELCEL presentado por HSBC | ||
| Surface: Hard | Date: Feb. 26 - Mar. 3 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Pauline Parmentier | Win | 6-4, 6-0 |
| Second Round | Arantxa Rus | Win | 5-7, 7-6 (8-6), 6-0 |
| Quarterfinals | Stefanie Voegele | Loss | 4-6, 7-5, 2-6 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 15 - Jan. 28 | Seed: 13 |
| Round | Opponent | W / L | Result |
| First Round | Shuai Zhang | Loss | 6-2, 6-7 (2-7), 2-6 |
| Sydney International | ||
| Surface: Hard | Date: Jan. 7 - Jan. 13 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Camila Giorgi | Loss | 3-6, 0-6 |
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