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| Hengqin Life WTA Elite Trophy | ||
| Surface: Hard | Date: Oct. 22 - Oct. 27 | Seed: 5 |
| Round | Opponent | W / L | Result |
| Round Robin | Madison Keys | Loss | 3-6, 4-6 6-4, 6-3 |
| Round Robin | Saisai Zheng | Win | 3-6, 4-6 6-4, 6-3 |
| China Open | ||
| Surface: Hard | Date: Sep. 28 - Oct. 6 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Elise Mertens | Loss | 2-6, 3-6 |
| Dongfeng Motor Wuhan Open | ||
| Surface: Hard | Date: Sep. 22 - Sep. 28 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Kristina Mladenovic | Win | 6-2, 6-2 |
| Second Round | Rebecca Peterson | Win | 6-0, 3-6, 6-1 |
| Third Round | Veronika Kudermetova | Win | 6-3, 6-1 |
| Quarterfinals | Ashleigh Barty | Loss | 6-7 (6-8), 6-3, 3-6 |
| Zhengzhou Open | ||
| Surface: Hard | Date: Sep. 9 - Sep. 15 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Jasmine Paolini | Win | 7-5, 6-1 |
| Second Round | Fiona Ferro | Win | 3-6, 6-1, 6-2 |
| Quarterfinals | Aryna Sabalenka | Win | 7-5, 5-7, 6-4 |
| Semifinals | Kristina Mladenovic | Win | 6-0, 6-3 |
| Final | Karolina Pliskova | Loss | 3-6, 2-6 |
| US Open | ||
| Surface: Hard | Date: Aug. 26 - Sep. 8 | Seed: 22 |
| Round | Opponent | W / L | Result |
| First Round | Tamara Zidansek | Win | 6-4, 4-6, 6-1 |
| Second Round | Ana Bogdan | Win | 6-2, 6-4 |
| Third Round | Anastasija Sevastova | Win | 6-4, 6-3 |
| Fourth Round | Serena Williams | Loss | 3-6, 4-6 |
| Western & Southern Womens Open | ||
| Surface: Hard | Date: Aug. 11 - Aug. 18 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Aryna Sabalenka | Loss | 1-6, 4-6 |
| Rogers Cup presented by National Bank | ||
| Surface: Hard | Date: Aug. 5 - Aug. 11 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Francesca Di Lorenzo | Loss | 4-6, 5-7 |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 1 - Jul. 14 | Seed: 24 |
| Round | Opponent | W / L | Result |
| First Round | Jennifer Brady | Win | 3-6, 6-3, 6-4 |
| Second Round | Anastasia Potapova | Win | 3-6, 6-3, 6-4 |
| Third Round | Danielle Collins | Win | 6-4, 3-6, 6-4 |
| Fourth Round | Elina Svitolina | Loss | 4-6, 2-6 |
| Nature Valley Classic | ||
| Surface: Grass | Date: Jun. 17 - Jun. 23 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Ekaterina Alexandrova | Win | 6-3, 7-5 |
| Second Round | Margarita Gasparyan | Win | 6-3, 7-6 (7-4) |
| Quarterfinals | Jelena Ostapenko | Win | 6-7 (4-7), 7-5, 6-1 |
| Semifinals | Julia Goerges | Loss | 4-6, 3-6 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 26 - Jun. 9 | Seed: 31 |
| Round | Opponent | W / L | Result |
| First Round | Ons Jabeur | Win | 6-1, 6-2 |
| Second Round | Kristina Mladenovic | Win | 6-2, 6-1 |
| Third Round | Karolina Pliskova | Win | 6-3, 6-3 |
| Fourth Round | Kaia Kanepi | Win | 5-7, 6-2, 6-4 |
| Quarterfinals | Marketa Vondrousova | Loss | 6-7 (1-7), 5-7 |
| Mutua Madrid Open | ||
| Surface: Red Clay | Date: May 4 - May 12 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Garbine Muguruza | Win | 7-5, 7-6 (7-2) |
| Second Round | Angelique Kerber | Win | Retired |
| Third Round | Donna Vekic | Win | 4-6, 6-3, 3-0 Retired |
| Quarterfinals | Sloane Stephens | Loss | 4-6, 3-6 |
| TEB BNP Paribas Istanbul Cup | ||
| Surface: Clay | Date: Apr. 22 - Apr. 28 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Tamara Zidansek | Win | 3-6, 6-1, 6-3 |
| Second Round | Ana Bogdan | Win | 4-6, 7-5, 6-3 |
| Quarterfinals | Kristina Mladenovic | Win | 7-6 (7-4), 4-6, 7-6 (7-2) |
| Semifinals | Margarita Gasparyan | Win | 6-1, 0-0 Retired |
| Final | Marketa Vondrousova | Win | 1-6, 6-4, 6-1 |
| Volvo Car Open | ||
| Surface: Green Clay | Date: Apr. 1 - Apr. 7 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Amanda Anisimova | Win | 6-4, 2-6, 6-1 |
| Second Round | Mandy Minella | Win | 6-3, 6-3 |
| Third Round | Jessica Pegula | Win | 2-6, 6-3, 6-2 |
| Quarterfinals | Belinda Bencic | Win | 6-3, 6-4 |
| Semifinals | Caroline Wozniacki | Loss | 3-6, 4-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 19 - Mar. 31 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Shuai Zhang | Win | 6-2, 6-1 |
| Second Round | Karolina Pliskova | Loss | 3-6, 4-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 6 - Mar. 17 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Magda Linette | Loss | 3-6, 6-4, 6-7 (5-7) |
| Dubai Duty Free Tennis Championships | ||
| Surface: Hard | Date: Feb. 17 - Feb. 23 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Katerina Siniakova | Loss | 4-6, 3-6 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 14 - Jan. 27 | Seed: 31 |
| Round | Opponent | W / L | Result |
| First Round | Heather Watson | Win | 6-1, 6-2 |
| Second Round | Marketa Vondrousova | Win | 6-4, 7-5 |
| Third Round | Sloane Stephens | Loss | 6-7 (6-8), 6-7 (5-7) |
| ASB Classic | ||
| Surface: Hard | Date: Dec. 31 - Jan. 12 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Sofia Kenin | Loss | 5-7, 6-2, 2-6 |
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