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| Volvo Car Open | ||
| Surface: Green Clay | Date: Apr. 5 - Apr. 11 | Seed: 10 |
| Round | Opponent | W / L | Result |
| First Round | Catherine McNally | Loss | 4-6, 0-0 Retired |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 23 - Apr. 4 | Seed: 21 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Kaia Kanepi | Win | 6-4, 6-0 |
| Third Round | Sara Sorribes Tormo | Loss | 1-6, 6-3, 2-6 |
| Dubai Duty Free Tennis Championships | ||
| Surface: Hard | Date: Mar. 7 - Mar. 13 | Seed: 14 |
| Round | Opponent | W / L | Result |
| First Round | Saisai Zheng | Win | 6-0, 6-4 |
| Second Round | Ons Jabeur | Loss | 6-7 (6-8), 6-4, 2-6 |
| Qatar Total Open 2021 | ||
| Surface: Hard | Date: Mar. 1 - Mar. 6 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Laura Siegemund | Loss | 6-7 (7-9), 6-7 (5-7) |
| Australian Open | ||
| Surface: Hard | Date: Feb. 8 - Feb. 21 | Seed: 17 |
| Round | Opponent | W / L | Result |
| First Round | Vera Zvonareva | Win | 4-6, 6-4, 6-4 |
| Second Round | Fiona Ferro | Loss | 4-6, 4-6 |
| Grampians Trophy | ||
| Surface: Hard | Date: Feb. 3 - Feb. 7 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Barbora Krejcikova | Loss | 6-4, 2-6, 6-10 |
| Abu Dhabi WTA Women's Tennis Open | ||
| Surface: Hard | Date: Jan. 6 - Jan. 13 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Lucrezia Stefanini | Win | 6-1, 6-3 |
| Second Round | Xiyu Wang | Win | 6-4, 6-4 |
| Third Round | Daria Kasatkina | Win | 6-3, 6-4 |
| Quarterfinals | Aryna Sabalenka | Loss | 4-6, 6-4, 3-6 |
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