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| US Open | ||
| Surface: Hard | Date: Aug. 26 - Sep. 8 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Gregoire Barrere | Loss | 6-7 (4-7), 4-6, 6-4, 7-6 (7-5), 6-7 (2-7) |
| Coupe Rogers presentee par Banque Nationale | ||
| Surface: Hard | Date: Aug. 5 - Aug. 11 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Marton Fucsovics | Win | 5-7, 6-2, 6-3 |
| Second Round | Alexander Zverev | Loss | 6-7 (4-7), 4-6 |
| Abierto Mexicano de Tenis Mifel presentado por Cinemex | ||
| Surface: Hard | Date: Jul. 29 - Aug. 3 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Gregoire Barrere | Win | 7-6 (7-5), 6-0 |
| Second Round | Mikhail Kukushkin | Loss | 5-7, 5-7 |
| BB&T Atlanta Open | ||
| Surface: Hard | Date: Jul. 22 - Jul. 28 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Jordan Thompson | Win | 7-6 (7-3), 4-6, 6-3 |
| Second Round | Soon Woo Kwon | Win | 6-3, 6-4 |
| Quarterfinals | Alexei Popyrin | Win | 7-5, 6-4 |
| Semifinals | Taylor Fritz | Loss | 1-6, 6-3, 3-6 |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 1 - Jul. 14 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Denis Istomin | Win | 6-2, 6-4, 6-4 |
| Second Round | Kei Nishikori | Loss | 4-6, 4-6, 0-6 |
| Nature Valley International | ||
| Surface: Grass | Date: Jun. 23 - Jun. 29 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Jeremy Chardy | Win | 6-3, 7-6 (7-4) |
| Second Round | Kyle Edmund | Loss | 2-6, 2-6 |
| Fever-Tree Championships | ||
| Surface: Grass | Date: Jun. 17 - Jun. 23 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Kevin Anderson | Loss | 6-4, 6-7 (5-7), 4-6 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 26 - Jun. 9 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Elliot Benchetrit | Loss | 3-6, 0-6, 2-6 |
| Open Parc Auvergne-Rhone-Alpes Lyon | ||
| Surface: Clay | Date: May 19 - May 25 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Ugo Humbert | Loss | 1-6, 3-6 |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 12 - May 19 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | John Millman | Win | 3-6, 6-3, 6-4 |
| Second Round | Borna Coric | Loss | 2-6, 2-6 |
| Barcelona Open Banc Sabadell | ||
| Surface: Clay | Date: Apr. 22 - Apr. 28 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Albert Ramos-Vinolas | Loss | 2-6, 2-6 |
| Rolex Monte-Carlo Masters | ||
| Surface: Clay | Date: Apr. 14 - Apr. 21 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Adrian Mannarino | Win | 6-4, 6-3 |
| Second Round | Marton Fucsovics | Win | 7-6 (7-3), 6-3 |
| Third Round | Lorenzo Sonego | Loss | 2-6, 5-7 |
| Fayez Sarofim & Co. US Men's Clay Court Championship | ||
| Surface: Clay | Date: Apr. 8 - Apr. 14 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Janko Tipsarevic | Loss | 3-6, 4-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 19 - Mar. 31 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Jordan Thompson | Loss | 6-4, 6-7 (5-7), 3-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 6 - Mar. 17 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Felix Auger-Aliassime | Loss | 3-6, 2-6 |
| Abierto Mexicano TELCEL presentado por HSBC | ||
| Surface: Hard | Date: Feb. 25 - Mar. 3 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Yoshihito Nishioka | Win | 6-2, 2-6, 6-2 |
| Second Round | Diego Schwartzman | Win | 7-6 (7-5), 4-6, 6-3 |
| Quarterfinals | Mackenzie McDonald | Win | 6-3, 6-2 |
| Semifinals | Alexander Zverev | Loss | 6-7 (0-7), 3-6 |
| Rio Open presented by Claro HDTV | ||
| Surface: Clay | Date: Feb. 18 - Feb. 24 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Dusan Lajovic | Win | 6-2, 6-1 |
| Second Round | Jaume Munar | Loss | 6-7 (6-8), 7-5, 6-7 (4-7) |
| Cordoba Open | ||
| Surface: Clay | Date: Feb. 4 - Feb. 10 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Pedro Cachin | Loss | 4-6, 4-6 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 14 - Jan. 27 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Taylor Fritz | Loss | 3-6, 6-7 (6-8), 2-6 |
| ASB Classic | ||
| Surface: Hard | Date: Dec. 31 - Jan. 12 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Benoit Paire | Win | 6-3, 6-2 |
| Second Round | Joao Sousa | Win | 7-6 (7-5), 6-4 |
| Quarterfinals | Taylor Fritz | Win | 7-6 (7-3), 6-3 |
| Semifinals | Jan-Lennard Struff | Win | 7-5, 4-6, 6-3 |
| Final | Tennys Sandgren | Loss | 4-6, 2-6 |
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