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| Zhuhai Championships | ||
| Surface: Hard | Date: Sep. 20 - Sep. 26 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Juncheng Shang | Win | 6-4, 6-7 (3-7), 6-3 |
| Second Round | Kimmer Coppejans | Win | 4-6, 6-3, 6-2 |
| Quarterfinals | Karen Khachanov |
| US Open | ||
| Surface: Hard | Date: Aug. 28 - Sep. 10 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Felix Auger-Aliassime | Win | 7-6 (7-5), 4-6, 6-1, 6-4 |
| Second Round | Borna Gojo | Loss | 3-6, 4-6, 4-6 |
| Western & Southern Open | ||
| Surface: Hard | Date: Aug. 13 - Aug. 20 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Yannick Hanfmann | Win | 7-5, 6-1 |
| Second Round | Holger Rune | Win | 6-4, 2-0 Retired |
| Third Round | Adrian Mannarino | Loss | 4-6, 0-3 Retired |
| Omnium National Bank presented by Rogers | ||
| Surface: Hard | Date: Aug. 7 - Aug. 13 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Aslan Karatsev | Win | 6-3, 6-4 |
| Second Round | Andrey Rublev | Win | 6-4, 6-3 |
| Third Round | Milos Raonic | Win | 6-3, 6-3 |
| Quarterfinals | Alejandro Davidovich Fokina | Loss | 4-6, 2-6 |
| Citi Open | ||
| Surface: Hard | Date: Jul. 31 - Aug. 6 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Diego Schwartzman | Win | 6-3, 6-3 |
| Second Round | Grigor Dimitrov | Loss | 6-7 (6-8), 2-6 |
| Infosys Hall of Fame Open | ||
| Surface: Grass | Date: Jul. 17 - Jul. 23 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Li Tu | Win | |
| Quarterfinals | Alex Michelsen | Loss |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 3 - Jul. 16 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Alexander Bublik | Loss |
| Rothesay International Eastbourne | ||
| Surface: Grass | Date: Jun. 26 - Jul. 1 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Marco Cecchinato | Win | |
| Second Round | Taylor Fritz | Win | |
| Quarterfinals | Mikael Ymer | Win | |
| Semifinals | Francisco Cerundolo | Loss |
| Cinch Championships | ||
| Surface: Grass | Date: Jun. 19 - Jun. 25 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Diego Schwartzman | Loss |
| Libema Open | ||
| Surface: Grass | Date: Jun. 12 - Jun. 18 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Ilya Ivashka | Win | |
| Second Round | Borna Coric | Win | |
| Quarterfinals | Rinky Hijikata | Loss |
| French Open | ||
| Surface: Red Clay | Date: May 28 - Jun. 11 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Sebastian Korda | Loss |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 10 - May 21 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Marco Cecchinato | Loss |
| Mutua Madrid Open | ||
| Surface: Hard | Date: Apr. 26 - May 7 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Bernabe Zapata Miralles | Loss |
| Barcelona Open Banc Sabadell | ||
| Surface: Clay | Date: Apr. 17 - Apr. 23 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Ben Shelton | Loss |
| Rolex Monte-Carlo Masters | ||
| Surface: Clay | Date: Apr. 9 - Apr. 16 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Ivan Gakhov | Loss |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 22 - Apr. 2 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Daniel Elahi Galan | Win | |
| Second Round | Matteo Berrettini | Win | |
| Third Round | Quentin Halys | Loss |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 8 - Mar. 19 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Filip Krajinovic | Win | |
| Second Round | Holger Rune | Loss |
| Abierto Mexicano Telcel presentado por HSBC | ||
| Surface: Hard | Date: Feb. 26 - Mar. 4 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Luciano Darderi | Win | |
| Second Round | Brandon Nakashima | Win | |
| Quarterfinals | Tommy Paul | Loss |
| Delray Beach Open | ||
| Surface: Hard | Date: Feb. 13 - Feb. 19 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Taro Daniel | Win | |
| Second Round | Yoshihito Nishioka | Win | |
| Quarterfinals | Michael Mmoh | Win | |
| Semifinals | Taylor Fritz | Loss |
| Dallas Open | ||
| Surface: Hard | Date: Feb. 6 - Feb. 12 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Fernando Verdasco | Win | |
| Second Round | Frances Tiafoe | Loss |
| Australian Open | ||
| Surface: Hard | Date: Jan. 15 - Jan. 29 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Brandon Nakashima | Win | |
| Second Round | Rafael Nadal | Win | |
| Third Round | Yoshihito Nishioka | Loss |
| Adelaide International 2 | ||
| Surface: Hard | Date: Jan. 9 - Jan. 14 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Daniel Evans | Win | |
| Second Round | Mikael Ymer | Loss |
| Adelaide International 1 | ||
| Surface: Hard | Date: Jan. 1 - Jan. 8 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Daniel Elahi Galan | Win | |
| Second Round | Yoshihito Nishioka | Loss |
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