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| Nature Valley International | ||
| Surface: Grass | Date: Jun. 23 - Jun. 29 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Cameron Norrie |
| Fever-Tree Championships | ||
| Surface: Grass | Date: Jun. 17 - Jun. 23 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Stefanos Tsitsipas | Loss | 3-6, 5-7 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 26 - Jun. 9 | Seed: 28 |
| Round | Opponent | W / L | Result |
| First Round | Jeremy Chardy | Win | 7-6 (7-1), 5-7, 6-4, 4-6, 7-5 |
| Second Round | Pablo Cuevas | Loss | 6-7 (3-7), 3-6, 1-2 Retired |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 12 - May 19 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Fernando Verdasco | Loss | 6-4, 4-6, 2-6 |
| Mutua Madrid Open | ||
| Surface: Red Clay | Date: May 4 - May 12 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Fabio Fognini | Loss | 4-6, 3-6 |
| BMW Open by FWU | ||
| Surface: Red Clay | Date: Apr. 29 - May 5 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Denis Kudla | Loss | 4-6, 3-6 |
| Rolex Monte-Carlo Masters | ||
| Surface: Clay | Date: Apr. 14 - Apr. 21 | Seed: 17 |
| Round | Opponent | W / L | Result |
| First Round | Diego Schwartzman | Loss | 6-4, 3-6, 1-6 |
| Grand Prix Hassan II | ||
| Surface: Red Clay | Date: Apr. 8 - Apr. 14 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Ugo Humbert | Win | 6-3, 6-2 |
| Second Round | Jo-Wilfried Tsonga | Loss | 6-7 (6-8), 3-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 19 - Mar. 31 | Seed: 19 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Ilya Ivashka | Win | 6-3, 6-2 |
| Third Round | Milos Raonic | Win | 6-4, 6-4 |
| Fourth Round | John Isner | Loss | 6-7 (5-7), 6-7 (3-7) |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 6 - Mar. 17 | Seed: 22 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Nicolas Jarry | Win | 6-2, 6-0 |
| Third Round | Radu Albot | Win | 6-3, 6-3 |
| Fourth Round | Roger Federer | Loss | 1-6, 4-6 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 14 - Jan. 27 | Seed: 13 |
| Round | Opponent | W / L | Result |
| First Round | Tomas Berdych | Loss | 3-6, 0-6, 5-7 |
| Brisbane International presented by Suncorp | ||
| Surface: Hard | Date: Dec. 31 - Jan. 6 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Yasutaka Uchiyama | Loss | 6-7 (6-7), 4-6 |
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