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| US Open | ||
| Surface: Hard | Date: Aug. 30 - Sep. 12 | Seed: 27 |
| Round | Opponent | W / L | Result |
| First Round | Mackenzie McDonald | Loss | 2-6, 5-7, 3-6 |
| Western & Southern Open | ||
| Surface: Hard | Date: Aug. 15 - Aug. 22 | Seed: 15 |
| Round | Opponent | W / L | Result |
| First Round | Guido Pella | Loss | 3-6, 3-6 |
| NOVENTI OPEN | ||
| Surface: Grass | Date: Jun. 14 - Jun. 20 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Corentin Moutet | Loss | 6-1, 5-7, 0-0 Retired |
| Roland Garros | ||
| Surface: Red Clay | Date: May 30 - Jun. 13 | Seed: 13 |
| Round | Opponent | W / L | Result |
| First Round | Lorenzo Musetti | Loss | 0-6, 5-7, 6-7 (3-7) |
| Open Parc Auvergne-Rhone-Alpes Lyon | ||
| Surface: Clay | Date: May 17 - May 23 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Aljaz Bedene | Loss | 6-7 (4-7), 3-6 |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 9 - May 16 | Seed: 12 |
| Round | Opponent | W / L | Result |
| First Round | Salvatore Caruso | Win | 6-4, 6-1 |
| Second Round | Federico Delbonis | Loss | 2-6, 1-6 |
| Barcelona Open Banc Sabadell | ||
| Surface: Clay | Date: Apr. 19 - Apr. 25 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Pierre-Hugues Herbert | Win | 6-2, 6-4 |
| Third Round | Cameron Norrie | Loss | 0-6, 5-3 Retired |
| Rolex Monte-Carlo Masters | ||
| Surface: Clay | Date: Apr. 11 - Apr. 18 | Seed: 11 |
| Round | Opponent | W / L | Result |
| First Round | Marin Cilic | Win | 6-4, 3-6, 6-0 |
| Second Round | Marco Cecchinato | Win | 6-4, 6-0 |
| Third Round | Alexander Zverev | Win | 6-4, 7-6 (9-7) |
| Quarterfinals | Daniel Evans | Loss | 7-5, 3-6, 4-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 23 - Apr. 4 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | James Duckworth | Loss | 3-6, 1-6 |
| Dubai Duty Free Tennis Championships | ||
| Surface: Hard | Date: Mar. 14 - Mar. 20 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Kei Nishikori | Loss | 3-6, 6-7 (3-7) |
| Qatar ExxonMobil Open | ||
| Surface: Hard | Date: Mar. 8 - Mar. 13 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Filip Krajinovic | Win | 6-4, 6-4 |
| Second Round | Taylor Fritz | Loss | 1-6, 7-5, 6-7 (9-11) |
| ABN AMRO World Tennis Tournament | ||
| Surface: Hard | Date: Mar. 1 - Mar. 7 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Jan-Lennard Struff | Win | 6-4, 6-0 |
| Second Round | Jeremy Chardy | Loss | 6-7 (3-7), 6-7 (5-7) |
| Open Sud de France | ||
| Surface: Hard | Date: Feb. 22 - Feb. 28 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Benjamin Bonzi | Win | 4-6, 6-4, 7-5 |
| Quarterfinals | Lorenzo Sonego | Win | 6-4, 6-4 |
| Semifinals | Egor Gerasimov | Win | 6-4, 2-6, 6-4 |
| Final | Roberto Bautista Agut | Win | 5-7, 6-4, 6-2 |
| Australian Open | ||
| Surface: Hard | Date: Feb. 8 - Feb. 21 | Seed: 13 |
| Round | Opponent | W / L | Result |
| First Round | Alexei Popyrin | Loss | 6-3, 4-6, 7-6 (7-4), 6-7 (6-8), 3-6 |
| Great Ocean Road Open | ||
| Surface: Hard | Date: Feb. 1 - Feb. 7 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Carlos Alcaraz | Loss | 3-6, 3-6 |
| Antalya Open | ||
| Surface: Grass | Date: Jan. 7 - Jan. 13 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Pierre-Hugues Herbert | Win | 3-6, 7-5, 6-0 |
| Second Round | Nicola Kuhn | Win | 6-0, 6-2 |
| Quarterfinals | Stefano Travaglia | Win | 6-3, 6-2 |
| Semifinals | Alex De Minaur | Loss | 4-6, 6-3, 2-6 |
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