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| Shanghai Rolex Masters | ||
| Surface: Hard | Date: Oct. 8 - Oct. 15 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Ze Zhang | Win | 6-2, 6-3 |
| Second Round | Grigor Dimitrov | Loss | 6-3, 3-6, 6-7 (6-8) |
| Rakuten Japan Open Tennis Championships | ||
| Surface: Hard | Date: Oct. 2 - Oct. 8 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Yusuke Takahashi | Win | 6-4, 4-6, 6-4 |
| Second Round | Kevin Anderson | Win | 6-3, 1-6, 7-6 (7-2) |
| Quarterfinals | Marin Cilic | Loss | 2-6, 0-6 |
| US Open | ||
| Surface: Hard | Date: Aug. 28 - Sep. 10 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Tomas Berdych | Loss | 4-6, 2-6, 6-7 (4-7) |
| Western & Southern Open | ||
| Surface: Hard | Date: Aug. 13 - Aug. 20 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Gilles Muller | Loss | 4-6, 7-5, 6-7 (3-7) |
| Coupe Rogers | ||
| Surface: Hard | Date: Aug. 7 - Aug. 13 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Thomas Fabbiano | Win | 6-3, 7-5 |
| Second Round | Roberto Bautista Agut | Loss | 5-7, 2-6 |
| Citi Open | ||
| Surface: Hard | Date: Jul. 31 - Aug. 6 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Marcos Baghdatis | Loss | 4-6, 1-6 |
| BB&T Atlanta Open | ||
| Surface: Hard | Date: Jul. 24 - Jul. 30 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | John Millman | Win | 6-7 (2-7), 7-6 (7-4), 7-5 |
| Quarterfinals | Christopher Eubanks | Win | 6-1, 6-2 |
| Semifinals | Kyle Edmund | Win | 6-7 (5-7), 6-3, 6-4 |
| Final | John Isner | Loss | 6-7 (6-8), 6-7 (7-9) |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 3 - Jul. 16 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Borna Coric | Win | 7-6 (7-4), 6-4, 7-6 (8-6) |
| Second Round | Tomas Berdych | Loss | 4-6, 3-6, 7-6 (10-8), 3-6 |
| AEGON International Eastbourne | ||
| Surface: Grass | Date: Jun. 25 - Jul. 1 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Mischa Zverev | Loss | 4-6, 6-7 (9-11) |
| AEGON Championships | ||
| Surface: Grass | Date: Jun. 19 - Jun. 25 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Grigor Dimitrov | Loss | 3-6, 1-6 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 28 - Jun. 11 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Aljaz Bedene | Loss | 4-6, 0-6, 6-3, 1-6 |
| Banque Eric Sturdza Geneva Open | ||
| Surface: Clay | Date: May 21 - May 27 | Seed: 9 |
| Round | Opponent | W / L | Result |
| First Round | Janko Tipsarevic | Loss | 4-6, 6-7 (5-7) |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 14 - May 21 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Jared Donaldson | Win | 2-6, 7-6 (7-0), 6-3 |
| Second Round | Marin Cilic | Loss | 3-6, 2-6 |
| Mutua Madrid Open | ||
| Surface: Red Clay | Date: May 6 - May 14 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Bernard Tomic | Win | 7-5, 4-6, 6-2 |
| Second Round | Nick Kyrgios | Loss | 3-6, 3-6 |
| Millennium Estoril Open | ||
| Surface: Red Clay | Date: May 1 - May 7 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Guillermo Garcia-Lopez | Win | 6-3, 2-6, 6-2 |
| Second Round | Juan Martin Del Potro | Win | Retired |
| Quarterfinals | David Ferrer | Loss | 4-6, 0-6 |
| Gazprom Hungarian Open | ||
| Surface: Red Clay | Date: Apr. 24 - Apr. 30 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Andrey Kuznetsov | Loss | 6-7 (6-8), 3-6 |
| Monte-Carlo Rolex Masters | ||
| Surface: Clay | Date: Apr. 16 - Apr. 23 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Lucas Pouille | Loss | 2-6, 4-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 21 - Apr. 2 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Fabio Fognini | Loss | 4-6, 5-7 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 9 - Mar. 19 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Damir Dzumhur | Loss | 4-6, 6-3, 5-7 |
| Memphis Open | ||
| Surface: Hard | Date: Feb. 13 - Feb. 19 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Konstantin Kravchuk | Win | 6-3, 7-5 |
| Second Round | Sam Querrey | Win | 6-3, 6-1 |
| Quarterfinals | Damir Dzumhur | Win | 6-3, 6-4 |
| Semifinals | Donald Young | Win | 6-4, 6-4 |
| Final | Nikoloz Basilashvili | Win | 6-1, 6-4 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 15 - Jan. 29 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Nicolas Mahut | Win | 6-3, 6-4, 6-2 |
| Second Round | Tomas Berdych | Loss | 3-6, 6-7 (6-8), 2-6 |
| ASB Classic | ||
| Surface: Hard | Date: Jan. 2 - Jan. 14 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Guillermo Garcia-Lopez | Win | 6-1, 6-2 |
| Second Round | Jack Sock | Loss | 6-7 (5-7), 6-4, 1-6 |
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