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| BB&T Atlanta Open | ||
| Surface: Hard | Date: Jul. 21 - Jul. 27 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye |
| Wimbledon | ||
| Surface: Grass | Date: Jun. 23 - Jul. 6 | Seed: 20 |
| Round | Opponent | W / L | Result |
| First Round | Aljaz Bedene | Win | 6-3, 7-6 (7-0), 6-2 |
| Second Round | Edouard Roger-Vasselin | Win | 7-6 (7-0), 1-6, 6-3, 6-4 |
| Third Round | Fabio Fognini | Win | 4-6, 6-4, 2-6, 6-2, 6-1 |
| Fourth Round | Andy Murray | Loss | 4-6, 3-6, 6-7 (6-8) |
| AEGON Championships | ||
| Surface: Grass | Date: Jun. 9 - Jun. 15 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Daniel Evans | Win | 6-2, 6-3 |
| Third Round | Sergiy Stakhovsky | Win | 6-3, 3-6, 7-6 (7-4) |
| Quarterfinals | Radek Stepanek | Loss | 6-1, 3-6, 2-6 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 25 - Jun. 8 | Seed: 19 |
| Round | Opponent | W / L | Result |
| First Round | Stephane Robert | Win | 7-5, 6-3, 6-4 |
| Second Round | Axel Michon | Win | 6-2, 6-3, 6-2 |
| Third Round | Ivo Karlovic | Win | 6-3, 0-0 Retired |
| Fourth Round | David Ferrer | Loss | 3-6, 3-6, 7-6 (7-5), 1-6 |
| Monte-Carlo Rolex Masters | ||
| Surface: Clay | Date: Apr. 13 - Apr. 20 | Seed: 14 |
| Round | Opponent | W / L | Result |
| First Round | Gael Monfils | Loss | 4-6, 6-7 (4-7) |
| Grand Prix Hassan II | ||
| Surface: Red Clay | Date: Apr. 7 - Apr. 13 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Victor Hanescu | Loss | 4-6, 4-6 |
| Sony Open Tennis | ||
| Surface: Hard | Date: Mar. 18 - Mar. 30 | Seed: 17 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Horacio Zeballos | Win | 6-4, 6-3 |
| Third Round | Richard Gasquet | Loss | 3-6, 4-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 5 - Mar. 16 | Seed: 17 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Lleyton Hewitt | Win | 7-6 (7-5), 6-4 |
| Third Round | Evgeny Donskoy | Win | 4-6, 6-0, 6-3 |
| Fourth Round | Stanislas Wawrinka | Win | 7-6 (7-1), 4-6, 6-1 |
| Quarterfinals | Roger Federer | Loss | 5-7, 1-6 |
| Abierto Mexicano TELCEL | ||
| Surface: Hard | Date: Feb. 24 - Mar. 2 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Stephane Robert | Win | 6-2, 7-6 (9-7) |
| Second Round | Sam Querrey | Win | 7-6 (7-2), 6-4 |
| Quarterfinals | David Ferrer | Win | 2-6, 4-2 Retired |
| Semifinals | Alexandr Dolgopolov | Win | 6-1, 5-7, 6-4 |
| Final | Grigor Dimitrov | Loss | 6-7 (1-7), 6-3, 6-7 (5-7) |
| Delray Beach Open by The Venetian Las Vegas | ||
| Surface: Hard | Date: Feb. 17 - Feb. 23 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Tim Smyczek | Win | 4-6, 6-1, 6-3 |
| Second Round | Ivo Karlovic | Win | 1-0 Retired |
| Quarterfinals | Marinko Matosevic | Win | 6-7 (2-7), 6-3, 6-3 |
| Semifinals | Steve Johnson | Win | 6-2, 6-4 |
| Final | Marin Cilic | Loss | 6-7 (6-8), 7-6 (9-7), 4-6 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 13 - Jan. 26 | Seed: 19 |
| Round | Opponent | W / L | Result |
| First Round | Jiri Vesely | Win | 2-6, 6-7 (4-7), 6-4, 6-4, 6-4 |
| Second Round | Dominic Thiem | Win | 6-4, 6-3, 6-4 |
| Third Round | Edouard Roger-Vasselin | Win | 3-6, 4-6, 6-3, 7-6(7-5), 7-5 |
| Fourth Round | Tomas Berdych | Loss | 2-6, 2-6, 3-6 |
| Heineken Open | ||
| Surface: Hard | Date: Jan. 6 - Jan. 11 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Steve Johnson | Loss | 5-7, 4-6 |
| Brisbane International presented by Suncorp | ||
| Surface: Hard | Date: Dec. 29 - Jan. 5 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye |
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