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| BNP Paribas Masters | ||
| Surface: Hard | Date: Oct. 28 - Nov. 3 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Mikhail Youzhny | Win | 4-6, 7-6 (7-0), 2-1 Retired |
| Second Round | Roger Federer | Loss | 4-6, 4-6 |
| Valencia Open 500 | ||
| Surface: Hard | Date: Oct. 21 - Oct. 27 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Roberto Bautista Agut | Loss | 6-3, 6-7 (5-7), 3-6 |
| If Stockholm Open | ||
| Surface: Hard | Date: Oct. 14 - Oct. 20 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Kenny De Schepper | Loss | 6-7 (5-7), 6-4, 3-6 |
| Shanghai Rolex Masters | ||
| Surface: Hard | Date: Oct. 6 - Oct. 13 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Victor Hanescu | Win | 4-6, 7-6 (7-5), 7-6 (7-4) |
| Second Round | Stanislas Wawrinka | Loss | 4-6, 6-3, 6-7 (6-8) |
| Rakuten Japan Open Tennis Championships | ||
| Surface: Hard | Date: Sep. 29 - Oct. 6 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Lukas Lacko | Loss | 4-6, 6-7 (2-7) |
| US Open | ||
| Surface: Hard | Date: Aug. 26 - Sep. 9 | Seed: 17 |
| Round | Opponent | W / L | Result |
| First Round | Daniel Brands | Win | 7-5, 4-6, 6-2, 6-3 |
| Second Round | Marcos Baghdatis | Loss | 2-6, 2-6, 2-6 |
| Western & Southern Open | ||
| Surface: Hard | Date: Aug. 11 - Aug. 18 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Tommy Haas | Loss | 4-6, 4-6 |
| Rogers Cup | ||
| Surface: Hard | Date: Aug. 5 - Aug. 11 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Alexandr Dolgopolov | Loss | 6-7 (0-7), 4-6 |
| Citi Open | ||
| Surface: Hard | Date: Jul. 29 - Aug. 4 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | James Duckworth | Win | 6-3, 3-6, 6-4 |
| Third Round | Mardy Fish | Win | 7-6 (7-2), 6-1 |
| Quarterfinals | Juan Martin del Potro | Loss | 6-7 (0-7), 3-6 |
| BB&T Atlanta Open | ||
| Surface: | Date: Jul. 22 - Jul. 28 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Matthew Ebden | Win | 6-7 (7-9), 6-2, 6-2 |
| Quarterfinals | Denis Istomin | Win | 6-3, 3-6, 6-3 |
| Semifinals | Ryan Harrison | Win | 6-3, 7-6 (7-3) |
| Final | John Isner | Loss | 7-6 (7-3), 6-7 (2-7), 6-7 (2-7) |
| Claro Open Colombia | ||
| Surface: Hard | Date: Jul. 15 - Jul. 21 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Emilio Gomez | Win | 6-3, 7-6 (7-2) |
| Quarterfinals | Santiago Giraldo | Win | 6-3, 6-3 |
| Semifinals | Ivo Karlovic | Loss | 4-6, 7-6 (7-4), 3-6 |
| Wimbledon | ||
| Surface: Grass | Date: Jun. 24 - Jul. 7 | Seed: 27 |
| Round | Opponent | W / L | Result |
| First Round | Olivier Rochus | Win | 6-4, 6-2, 6-1 |
| Second Round | Michal Przysiezny | Win | 6-4, 7-6 (7-2), 6-4 |
| Third Round | Tomas Berdych | Loss | 6-3, 3-6, 4-6, 5-7 |
| AEGON International | ||
| Surface: Grass | Date: Jun. 17 - Jun. 22 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Julien Benneteau | Loss | 6-7 (4-7), 2-6 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 26 - Jun. 9 | Seed: 23 |
| Round | Opponent | W / L | Result |
| First Round | Illya Marchenko | Win | 6-3, 7-5, 6-4 |
| Second Round | Evgeny Donskoy | Win | 6-7 (8-10), 6-1, 7-5, 6-2 |
| Third Round | Milos Raonic | Win | 7-5, 7-6 (7-4), 6-3 |
| Fourth Round | David Ferrer | Loss | 3-6, 1-6, 1-6 |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 12 - May 19 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Jurgen Melzer | Win | 6-1, 6-2 |
| Second Round | Marin Cilic | Win | 6-3, 7-6 (9-7) |
| Third Round | Tomas Berdych | Loss | 5-7, 2-6 |
| Mutua Madrid Open | ||
| Surface: Red Clay | Date: May 4 - May 12 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Jesse Levine | Win | 6-2, 6-2 |
| Second Round | Juan Monaco | Win | 7-6 (7-5), 3-6, 6-4 |
| Third Round | Tomas Berdych | Loss | 6-7 (5-7), 5-7 |
| Monte-Carlo Rolex Masters | ||
| Surface: Clay | Date: Apr. 14 - Apr. 21 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Jerzy Janowicz | Win | 7-5, 7-6 (11-9) |
| Second Round | Marin Cilic | Loss | 2-6, 3-6 |
| Grand Prix Hassan II | ||
| Surface: Red Clay | Date: Apr. 8 - Apr. 14 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Pablo Carreno-Busta | Win | 6-3, 6-3 |
| Quarterfinals | Grega Zemlja | Win | 6-4, 6-4 |
| Semifinals | Martin Klizan | Win | 2-6, 6-4, 6-2 |
| Final | Tommy Robredo | Loss | 6-7 (6-8), 6-4, 3-6 |
| Sony Open Tennis | ||
| Surface: Hard | Date: Mar. 19 - Mar. 31 | Seed: 26 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Horacio Zeballos | Win | 6-3, 7-6 (7-4) |
| Third Round | Janko Tipsarevic | Loss | 6-4, 6-7 (5-7), 0-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 6 - Mar. 17 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Victor Hanescu | Win | 7-6 (8-6), 6-3 |
| Second Round | David Ferrer | Win | 3-6, 6-4, 6-3 |
| Third Round | Jarkko Nieminen | Win | 6-3, 6-1 |
| Fourth Round | Gilles Simon | Win | 6-3, 1-6, 6-4 |
| Quarterfinals | Tomas Berdych | Loss | 4-6, 4-6 |
| Delray Beach International Tennis Championships | ||
| Surface: Hard | Date: Feb. 25 - Mar. 3 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Tim Smyczek | Win | 6-3, 6-4 |
| Second Round | Yen-Hsun Lu | Win | 6-4, 3-6, 6-3 |
| Quarterfinals | John Isner | Loss | 2-6, 6-7 (1-7) |
| Australian Open | ||
| Surface: Hard | Date: Jan. 13 - Jan. 27 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Paolo Lorenzi | Win | 3-6, 7-6 (7-3), 6-3, 6-4 |
| Second Round | Andrey Kuznetsov | Win | 6-1, 7-5, 6-4 |
| Third Round | Fernando Verdasco | Win | 4-6, 6-3, 4-6, 7-6(7-4), 6-2 |
| Fourth Round | Tomas Berdych | Loss | 3-6, 2-6, 6-7 (13-15) |
| Apia International Sydney | ||
| Surface: Hard | Date: Jan. 5 - Jan. 12 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Aljaz Bedene | Win | 6-3, 3-6, 6-3 |
| Second Round | Feliciano Lopez | Win | 6-3, 6-4 |
| Quarterfinals | Denis Istomin | Win | 6-4, 6-3 |
| Semifinals | Julien Benneteau | Win | 3-6, 6-4, 7-6 (10-8) |
| Final | Bernard Tomic | Loss | 3-6, 7-6 (7-2), 3-6 |
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