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| BNP Paribas Masters | ||
| Surface: Hard | Date: Oct. 28 - Nov. 3 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Julien Benneteau | Win | 6-4, 6-2 |
| Second Round | Jo-Wilfried Tsonga | Win | 1-6, 7-6 (7-4), 7-6 (9-7) |
| Third Round | Richard Gasquet | Loss | 3-6, 2-6 |
| Swiss Indoors Basel | ||
| Surface: Hard | Date: Oct. 21 - Oct. 27 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Marco Chiudinelli | Win | 6-2, 6-4 |
| Second Round | Ivan Dodig | Loss | 1-6, 2-6 |
| Shanghai Rolex Masters | ||
| Surface: Hard | Date: Oct. 6 - Oct. 13 | Seed: 12 |
| Round | Opponent | W / L | Result |
| First Round | Grigor Dimitrov | Win | 6-3, 6-4 |
| Second Round | Jurgen Melzer | Win | 6-4, 3-6, 6-1 |
| Third Round | Jo-Wilfried Tsonga | Loss | 6-7 (5-7), 0-6 |
| Rakuten Japan Open Tennis Championships | ||
| Surface: Hard | Date: Sep. 29 - Oct. 6 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Jurgen Melzer | Win | 6-7 (4-7), 7-5, 6-2 |
| Second Round | Feliciano Lopez | Win | 7-6 (7-4), 6-0 |
| Quarterfinals | Nicolas Almagro | Loss | 6-7 (2-7), 7-5, 3-6 |
| US Open | ||
| Surface: Hard | Date: Aug. 26 - Sep. 9 | Seed: 11 |
| Round | Opponent | W / L | Result |
| First Round | Daniel Evans | Loss | 4-6, 4-6, 2-6 |
| Western & Southern Open | ||
| Surface: Hard | Date: Aug. 11 - Aug. 18 | Seed: 10 |
| Round | Opponent | W / L | Result |
| First Round | Feliciano Lopez | Loss | 4-6, 6-7 (4-7) |
| Rogers Cup | ||
| Surface: Hard | Date: Aug. 5 - Aug. 11 | Seed: 9 |
| Round | Opponent | W / L | Result |
| First Round | Peter Polansky | Win | 4-6, 6-4, 6-2 |
| Second Round | Andreas Seppi | Win | 4-6, 7-5, 6-1 |
| Third Round | Richard Gasquet | Loss | 6-1, 3-6, 3-6 |
| Citi Open | ||
| Surface: Hard | Date: Jul. 29 - Aug. 4 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Jack Sock | Win | 7-5, 6-2 |
| Third Round | Marcos Baghdatis | Loss | 1-6, 2-6 |
| Wimbledon | ||
| Surface: Grass | Date: Jun. 24 - Jul. 7 | Seed: 12 |
| Round | Opponent | W / L | Result |
| First Round | Matthew Ebden | Win | 6-2, 6-4, 6-3 |
| Second Round | Leonardo Mayer | Win | 7-6 (7-5), 6-4, 6-2 |
| Third Round | Andreas Seppi | Loss | 6-3, 2-6, 7-6 (7-4), 1-6, 4-6 |
| Gerry Weber Open | ||
| Surface: Grass | Date: Jun. 10 - Jun. 16 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Mikhail Youzhny | Loss | 1-6, 7-6 (7-4), 3-6 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 26 - Jun. 9 | Seed: 13 |
| Round | Opponent | W / L | Result |
| First Round | Jesse Levine | Win | 6-3, 6-2, 6-0 |
| Second Round | Grega Zemlja | Win | 6-1, 5-7, 6-1, 6-4 |
| Third Round | Benoit Paire | Win | 6-3, 6-7 (3-7), 6-4, 6-1 |
| Fourth Round | Rafael Nadal | Loss | 4-6, 1-6, 3-6 |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 12 - May 19 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Paolo Lorenzi | Win | 6-2, 6-4 |
| Second Round | Jeremy Chardy | Loss | 4-6, 1-6 |
| Mutua Madrid Open | ||
| Surface: Red Clay | Date: May 4 - May 12 | Seed: 14 |
| Round | Opponent | W / L | Result |
| First Round | Jurgen Melzer | Win | 6-3, 6-2 |
| Second Round | Viktor Troicki | Win | 7-5, 6-2 |
| Third Round | Roger Federer | Win | 6-4, 1-6, 6-2 |
| Quarterfinals | Pablo Andujar | Loss | 3-6, 5-7 |
| Barcelona Open Banc Sabadell | ||
| Surface: Clay | Date: Apr. 22 - Apr. 28 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Guillermo Olaso | Win | 6-1, 6-3 |
| Third Round | Albert Ramos | Loss | 4-6, 6-7 (4-7) |
| Sony Open Tennis | ||
| Surface: Hard | Date: Mar. 19 - Mar. 31 | Seed: 13 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Victor Hanescu | Win | 6-3, 6-3 |
| Third Round | Xavier Malisse | Win | 6-2, 7-5 |
| Fourth Round | David Ferrer | Loss | 4-6, 2-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 6 - Mar. 17 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Philipp Petzschner | Win | 6-3, 6-2 |
| Third Round | Carlos Berlocq | Loss | 2-6, 2-6 |
| Delray Beach International Tennis Championships | ||
| Surface: Hard | Date: Feb. 25 - Mar. 3 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Ivo Karlovic | Loss | 4-5 Retired |
| U.S. National Indoor Tennis Championships | ||
| Surface: Hard | Date: Feb. 17 - Feb. 24 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Illya Marchenko | Win | 6-4, 7-5 |
| Second Round | Donald Young | Win | 6-3, 6-3 |
| Quarterfinals | Marin Cilic | Win | 6-4, 6-2 |
| Semifinals | Marinko Matosevic | Win | 6-4, 0-0 Retired |
| Final | Feliciano Lopez | Win | 6-2, 6-3 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 13 - Jan. 27 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Victor Hanescu | Win | 6-7 (5-7), 6-3, 6-1, 6-3 |
| Second Round | Carlos Berlocq | Win | 7-6 (7-4), 6-4, 6-1 |
| Third Round | Evgeny Donskoy | Win | 7-6 (7-3), 6-2, 6-3 |
| Fourth Round | David Ferrer | Loss | 2-6, 1-6, 4-6 |
| Brisbane International | ||
| Surface: Hard | Date: Dec. 29 - Jan. 6 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Marinko Matosevic | Win | 7-5, 6-2 |
| Second Round | Tommy Robredo | Win | 6-3, 6-3 |
| Quarterfinals | Alexandr Dolgopolov | Win | 6-4, 7-6 (7-3) |
| Semifinals | Andy Murray | Loss | 4-6, 0-2 Retired |
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