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| BNP Paribas Masters | ||
| Surface: Hard | Date: Oct. 28 - Nov. 3 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Igor Sijsling | Win | 5-7, 6-1, 6-4 |
| Second Round | Juan Martin del Potro | Loss | 4-6, 6-7 (3-7) |
| Wimbledon | ||
| Surface: Grass | Date: Jun. 24 - Jul. 7 | Seed: 10 |
| Round | Opponent | W / L | Result |
| First Round | Marcos Baghdatis | Win | 6-3, 6-4, 6-4 |
| Second Round | Kenny De Schepper | Loss | Retired |
| AEGON Championships | ||
| Surface: Grass | Date: Jun. 10 - Jun. 16 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Ivan Dodig | Win | 6-3, 6-4 |
| Third Round | Feliciano Lopez | Win | 4-6, 7-6 (7-5), 7-5 |
| Quarterfinals | Tomas Berdych | Win | 7-5, 7-6 (7-4) |
| Semifinals | Lleyton Hewitt | Win | 6-4, 4-6, 6-2 |
| Final | Andy Murray | Loss | 7-5, 5-7, 3-6 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 26 - Jun. 9 | Seed: 10 |
| Round | Opponent | W / L | Result |
| First Round | Philipp Petzschner | Win | 6-1, 6-2, 6-3 |
| Second Round | Nick Kyrgios | Win | 6-4, 6-2, 6-2 |
| Third Round | Viktor Troicki | Loss | 6-7 (12-14), 4-6, 5-7 |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 12 - May 19 | Seed: 11 |
| Round | Opponent | W / L | Result |
| First Round | Andrey Golubev | Win | 6-4, 6-2 |
| Second Round | Kevin Anderson | Loss | 3-6, 6-7 (7-9) |
| Mutua Madrid Open | ||
| Surface: Red Clay | Date: May 4 - May 12 | Seed: 10 |
| Round | Opponent | W / L | Result |
| First Round | Pablo Andujar | Loss | 7-6 (8-6), 4-6, 1-6 |
| BMW Open | ||
| Surface: Red Clay | Date: Apr. 29 - May 5 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Ivan Dodig | Loss | 4-6, 2-6 |
| Monte-Carlo Rolex Masters | ||
| Surface: Clay | Date: Apr. 14 - Apr. 21 | Seed: 9 |
| Round | Opponent | W / L | Result |
| First Round | Horacio Zeballos | Win | 6-2, 6-7 (6-8), 6-2 |
| Second Round | Kevin Anderson | Win | 6-2, 6-3 |
| Third Round | Richard Gasquet | Loss | 5-7, 4-6 |
| Sony Open Tennis | ||
| Surface: Hard | Date: Mar. 19 - Mar. 31 | Seed: 9 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Santiago Giraldo | Win | 6-2, 7-6 (8-6) |
| Third Round | John Isner | Win | 6-3, 7-6 (7-3) |
| Fourth Round | Jo-Wilfried Tsonga | Win | 7-5, 7-6 (7-4) |
| Quarterfinals | Andy Murray | Loss | 4-6, 3-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 6 - Mar. 17 | Seed: 12 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Albert Ramos | Win | 7-6 (9-7), 6-2 |
| Third Round | Milos Raonic | Loss | 6-3, 4-6, 3-6 |
| U.S. National Indoor Tennis Championships | ||
| Surface: Hard | Date: Feb. 17 - Feb. 24 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Ivan Dodig | Win | 4-6, 6-2, 6-3 |
| Second Round | Igor Sijsling | Win | 7-6 (7-2), 3-6, 7-6 (9-7) |
| Quarterfinals | Kei Nishikori | Loss | 4-6, 2-6 |
| PBZ Zagreb Indoors | ||
| Surface: Hard | Date: Feb. 4 - Feb. 10 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Grega Zemlja | Win | 6-2, 6-3 |
| Quarterfinals | Blaz Kavcic | Win | 6-3, 7-6 (7-5) |
| Semifinals | Mikhail Youzhny | Win | 4-6, 6-4, 6-3 |
| Final | Jurgen Melzer | Win | 6-3, 6-1 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 13 - Jan. 27 | Seed: 12 |
| Round | Opponent | W / L | Result |
| First Round | Marinko Matosevic | Win | 6-4, 7-5, 6-2 |
| Second Round | Rajeev Ram | Win | 7-5, 6-2, 6-4 |
| Third Round | Andreas Seppi | Loss | 7-6 (7-2), 3-6, 6-2, 4-6, 2-6 |
| Aircel Chennai Open | ||
| Surface: Hard | Date: Dec. 31 - Jan. 6 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Sergiy Stakhovsky | Win | 4-6, 6-2, 6-3 |
| Quarterfinals | Benoit Paire | Loss | 4-6, 6-1, 5-7 |
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