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| Barclay's ATP World Tour Finals | ||
| Surface: Hard | Date: Nov. 9 - Nov. 16 | Seed: 9 |
| Round | Opponent | W / L | Result |
| Round Robin | Novak Djokovic | Loss | 1-6, 1-6 3-6, 1-6 3-6, 6-4, 3-6 |
| Round Robin | Tomas Berdych | Loss | 1-6, 1-6 3-6, 1-6 3-6, 6-4, 3-6 |
| Round Robin | Stan Wawrinka | Loss | 1-6, 1-6 3-6, 1-6 3-6, 6-4, 3-6 |
| Kremlin Cup | ||
| Surface: Hard | Date: Oct. 13 - Oct. 19 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Evgeny Donskoy | Win | 6-3, 3-6, 6-3 |
| Quarterfinals | Tommy Robredo | Win | 6-3, 6-3 |
| Semifinals | Mikhail Kukushkin | Win | 4-6, 6-3, 6-2 |
| Final | Roberto Bautista Agut | Win | 6-4, 6-4 |
| Shanghai Rolex Masters | ||
| Surface: Hard | Date: Oct. 5 - Oct. 12 | Seed: 9 |
| Round | Opponent | W / L | Result |
| First Round | Ivo Karlovic | Loss | 5-7, 6-2, 6-7 (2-7) |
| China Open | ||
| Surface: Hard | Date: Sep. 26 - Oct. 5 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Yan Bai | Win | 6-3, 6-4 |
| Second Round | Joao Sousa | Win | 6-3, 6-3 |
| Quarterfinals | Andy Murray | Loss | 1-6, 4-6 |
| US Open | ||
| Surface: Hard | Date: Aug. 25 - Sep. 8 | Seed: 14 |
| Round | Opponent | W / L | Result |
| First Round | Marcos Baghdatis | Win | 6-3, 3-1 Retired |
| Second Round | Illya Marchenko | Win | 7-6 (7-2), 6-2, 6-4 |
| Third Round | Kevin Anderson | Win | 6-3, 3-6, 6-3, 6-4 |
| Fourth Round | Gilles Simon | Win | 5-7, 7-6 (7-3), 6-4, 3-6, 6-3 |
| Quarterfinals | Tomas Berdych | Win | 6-2, 6-4, 7-6 (7-4) |
| Semifinals | Roger Federer | Win | 6-3, 6-4, 6-4 |
| Final | Kei Nishikori | Win | 6-3, 6-3, 6-3 |
| Western & Southern Financial Group Masters | ||
| Surface: Hard | Date: Aug. 10 - Aug. 17 | Seed: 14 |
| Round | Opponent | W / L | Result |
| First Round | Feliciano Lopez | Win | 6-3, 6-4 |
| Second Round | Fernando Verdasco | Win | 7-6 (8-6), 7-6 (7-5) |
| Third Round | Stan Wawrinka | Loss | 6-3, 0-6, 1-6 |
| Rogers Cup | ||
| Surface: Hard | Date: Aug. 4 - Aug. 10 | Seed: 15 |
| Round | Opponent | W / L | Result |
| First Round | Denis Istomin | Win | 6-2, 4-6, 7-5 |
| Second Round | Malek Jaziri | Win | 4-6, 6-0, 7-6 (7-4) |
| Third Round | Roger Federer | Loss | 6-7 (5-7), 7-6 (7-3), 4-6 |
| Vegeta Croatia Open Umag | ||
| Surface: Clay | Date: Jul. 21 - Jul. 27 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Igor Sijsling | Win | 7-5, 6-3 |
| Quarterfinals | Lukas Rosol | Win | 6-0, 6-2 |
| Semifinals | Tommy Robredo | Loss | 6-7 (10-12), 3-6 |
| Wimbledon | ||
| Surface: Grass | Date: Jun. 23 - Jul. 6 | Seed: 26 |
| Round | Opponent | W / L | Result |
| First Round | Paul-Henri Mathieu | Win | 6-4, 6-7 (2-7), 6-2, 6-1 |
| Second Round | Andreas Haider-Maurer | Win | 3-6, 6-1, 6-4, 6-4 |
| Third Round | Tomas Berdych | Win | 7-6 (7-5), 6-4, 7-6 (8-6) |
| Fourth Round | Jeremy Chardy | Win | 7-6 (10-8), 6-4, 6-4 |
| Quarterfinals | Novak Djokovic | Loss | 1-6, 6-3, 7-6 (7-4), 2-6, 2-6 |
| AEGON Championships | ||
| Surface: Grass | Date: Jun. 9 - Jun. 15 | Seed: 9 |
| Round | Opponent | W / L | Result |
| First Round | Marinko Matosevic | Loss | 4-6, 4-6 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 25 - Jun. 8 | Seed: 25 |
| Round | Opponent | W / L | Result |
| First Round | Pablo Andujar | Win | 6-0, 6-3, 7-6 (8-6) |
| Second Round | Tobias Kamke | Win | 6-3, 3-6, 6-3, 6-0 |
| Third Round | Novak Djokovic | Loss | 3-6, 2-6, 7-6 (7-2), 4-6 |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 11 - May 18 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Santiago Giraldo | Win | 6-4, 2-0 Retired |
| Second Round | Jurgen Melzer | Loss | 2-6, 7-6 (7-5), 3-6 |
| Mutua Madrilena Madrid Open | ||
| Surface: Red Clay | Date: May 3 - May 11 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Joao Sousa | Win | 6-1, 6-1 |
| Second Round | Paul-Henri Mathieu | Win | 6-4, 1-6, 6-2 |
| Third Round | Ernests Gulbis | Loss | 3-6, 4-6 |
| Barcelona Open BancSabadell | ||
| Surface: Clay | Date: Apr. 21 - Apr. 27 | Seed: 12 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Andrey Kuznetsov | Win | 6-1, 7-6 (7-2) |
| Third Round | Tommy Robredo | Win | 7-5, 6-7 (3-7), 7-6 (7-5) |
| Quarterfinals | Kei Nishikori | Loss | 1-6, 3-6 |
| Monte-Carlo Rolex Masters | ||
| Surface: Clay | Date: Apr. 13 - Apr. 20 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Marinko Matosevic | Win | 6-1, 3-6, 6-2 |
| Second Round | Stanislas Wawrinka | Loss | 0-6, 2-6 |
| Sony Open Tennis | ||
| Surface: Hard | Date: Mar. 18 - Mar. 30 | Seed: 25 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Edouard Roger-Vasselin | Loss | 2-6, 6-7 (5-7) |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 5 - Mar. 16 | Seed: 24 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Paolo Lorenzi | Win | 6-2, 6-2 |
| Third Round | Tommy Robredo | Win | 6-4, 6-3 |
| Fourth Round | Novak Djokovic | Loss | 6-1, 2-6, 3-6 |
| Delray Beach Open by The Venetian Las Vegas | ||
| Surface: Hard | Date: Feb. 17 - Feb. 23 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Benjamin Becker | Win | 6-1, 6-3 |
| Second Round | Ryan Harrison | Win | 6-3, 6-4 |
| Quarterfinals | Teymuraz Gabashvili | Win | 6-2, 6-3 |
| Semifinals | John Isner | Win | 7-6 (7-5), 6-3 |
| Final | Kevin Anderson | Win | 7-6 (8-6), 6-7 (7-9), 6-4 |
| ABN AMRO World Tennis Tournament | ||
| Surface: Hard | Date: Feb. 10 - Feb. 16 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Lukas Rosol | Win | 6-2, 6-2 |
| Second Round | Jo-Wilfried Tsonga | Win | 6-4, 6-4 |
| Quarterfinals | Andy Murray | Win | 6-3, 6-4 |
| Semifinals | Igor Sijsling | Win | 5-7, 6-3, 6-2 |
| Final | Tomas Berdych | Loss | 4-6, 2-6 |
| PBZ Zagreb Indoors | ||
| Surface: Hard | Date: Feb. 3 - Feb. 9 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Mate Delic | Win | 6-4, 6-4 |
| Second Round | Dusan Lajovic | Win | 6-4, 7-5 |
| Quarterfinals | Ivan Dodig | Win | 7-5, 6-4 |
| Semifinals | Bjorn Phau | Win | 6-3, 6-4 |
| Final | Tommy Haas | Win | 6-3, 6-4 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 13 - Jan. 26 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Marcel Granollers | Win | 4-6, 4-6, 6-3, 6-3, 6-2 |
| Second Round | Gilles Simon | Loss | 6-4, 6-7 (3-7), 7-6 (7-5), 1-6, 2-6 |
| Apia International Sydney | ||
| Surface: Hard | Date: Jan. 5 - Jan. 11 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Jan-Lennard Struff | Win | 3-6, 6-3, 6-3 |
| Second Round | Denis Istomin | Loss | 3-6, 4-6 |
| Brisbane International presented by Suncorp | ||
| Surface: Hard | Date: Dec. 29 - Jan. 5 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Denis Istomin | Win | 6-7 (3-7), 7-6 (7-5), 6-4 |
| Second Round | Grigor Dimitrov | Win | 7-5, 7-5 |
| Quarterfinals | Kei Nishikori | Loss | 4-6, 7-5, 2-6 |
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