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| Wimbledon | ||
| Surface: Grass | Date: Jun. 23 - Jul. 6 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Joao Sousa | Win | 6-3, 6-4, 6-3 |
| Second Round | Yen-Hsun Lu | Win | 7-6 (8-6), 6-3, 3-6, 7-5 |
| Third Round | Denis Istomin | Win | 6-3, 6-3, 6-4 |
| Fourth Round | Feliciano Lopez | Win | 7-6 (7-5), 7-6 (9-7), 6-3 |
| Quarterfinals | Roger Federer | Loss | 6-3, 6-7 (5-7), 4-6, 4-6 |
| AEGON Championships | ||
| Surface: Grass | Date: Jun. 9 - Jun. 15 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Marcos Baghdatis | Win | 3-2 Retired |
| Third Round | Sam Querrey | Win | 6-2, 6-2 |
| Quarterfinals | Marinko Matosevic | Win | 7-5, 6-3 |
| Semifinals | Grigor Dimitrov | Loss | 2-6, 4-6 |
| French Open | ||
| Surface: Red Clay | Date: May 25 - Jun. 8 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Guillermo Garcia-Lopez | Loss | 4-6, 7-5, 2-6, 0-6 |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 11 - May 18 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Pere Riba | Win | 6-0, 6-3 |
| Third Round | Tommy Haas | Loss | 7-5, 2-6, 3-6 |
| Mutua Madrid Open | ||
| Surface: Red Clay | Date: May 3 - May 11 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Dominic Thiem | Loss | 6-1, 2-6, 4-6 |
| Monte-Carlo Rolex Masters | ||
| Surface: Clay | Date: Apr. 13 - Apr. 20 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Marin Cilic | Win | 6-0, 6-2 |
| Third Round | Nicolas Almagro | Win | Retired |
| Quarterfinals | Milos Raonic | Win | 7-6 (7-5), 6-2 |
| Semifinals | David Ferrer | Win | 6-1, 7-6 (7-3) |
| Final | Roger Federer | Win | 4-6, 7-6 (7-5), 6-2 |
| Sony Open Tennis | ||
| Surface: Hard | Date: Mar. 18 - Mar. 30 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Daniel Gimeno-Traver | Win | 6-0, 3-6, 6-3 |
| Third Round | Edouard Roger-Vasselin | Win | 7-5, 6-4 |
| Fourth Round | Alexandr Dolgopolov | Loss | 4-6, 6-3, 1-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 5 - Mar. 16 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Ivo Karlovic | Win | 6-3, 7-5 |
| Third Round | Andreas Seppi | Win | 6-0, 6-2 |
| Fourth Round | Kevin Anderson | Loss | 6-7 (1-7), 6-4, 1-6 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 12 - Jan. 26 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Andrey Golubev | Win | 6-4, 4-1 Retired |
| Second Round | Alejandro Falla | Win | 6-3, 6-3, 6-7 (4-7), 6-4 |
| Third Round | Vasek Pospisil | Win | Retired |
| Fourth Round | Tommy Robredo | Win | 6-3, 7-6 (7-3), 7-6 (7-5) |
| Quarterfinals | Novak Djokovic | Win | 2-6, 6-4, 6-2, 3-6, 9-7 |
| Semifinals | Tomas Berdych | Win | 6-3, 6-7 (1-7), 7-6 (7-3), 7-6(7-4) |
| Final | Rafael Nadal | Win | 6-3, 6-2, 3-6, 6-3 |
| Aircel Chennai Open | ||
| Surface: Hard | Date: Dec. 30 - Jan. 5 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Benjamin Becker | Win | 6-3, 6-1 |
| Quarterfinals | Aljaz Bedene | Win | 6-2, 6-1 |
| Semifinals | Vasek Pospisil | Win | 6-4, 5-5 Retired |
| Final | Edouard Roger-Vasselin | Win | 7-5, 6-2 |
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