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| French Open | ||
| Surface: Red Clay | Date: May 28 - Jun. 11 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Alexandre Muller | Win | 6-1, 6-4, 6-1 |
| Second Round | Daniel Altmaier | Loss | 7-6 (7-0), 6-7 (7-9), 6-1, 6-7 (4-7), 5-7 |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 10 - May 21 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Thanasi Kokkinakis | Win | 6-1, 6-4 |
| Third Round | Alexander Shevchenko | Win | 6-3, 6-7 (4-7), 6-2 |
| Fourth Round | Francisco Cerundolo | Loss | 7-6 (7-3), 2-6, 2-6 |
| Barcelona Open Banc Sabadell | ||
| Surface: Clay | Date: Apr. 17 - Apr. 23 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Diego Schwartzman | Win | 6-2, 6-4 |
| Third Round | Yoshihito Nishioka | Win | 6-1, 4-6, 6-3 |
| Quarterfinals | Lorenzo Musetti | Loss | Retired |
| Rolex Monte-Carlo Masters | ||
| Surface: Clay | Date: Apr. 9 - Apr. 16 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Diego Schwartzman | Win | 6-0, 3-1 Retired |
| Third Round | Hubert Hurkacz | Win | 3-6, 7-6 (8-6), 6-1 |
| Quarterfinals | Lorenzo Musetti | Win | 6-2, 6-2 |
| Semifinals | Holger Rune | Loss | 6-1, 5-7, 5-7 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 22 - Apr. 2 | Seed: 10 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Laslo Djere | Win | 6-4, 6-2 |
| Third Round | Grigor Dimitrov | Win | 6-3, 6-4 |
| Fourth Round | Andrey Rublev | Win | 6-2, 6-4 |
| Quarterfinals | Emil Ruusuvuori | Win | 6-3, 6-1 |
| Semifinals | Carlos Alcaraz | Win | 6-7 (4-7), 6-4, 6-2 |
| Final | Daniil Medvedev | Loss | 5-7, 3-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 8 - Mar. 19 | Seed: 11 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Richard Gasquet | Win | 6-3, 7-6 (7-2) |
| Third Round | Adrian Mannarino | Win | 7-6 (9-7), 6-4 |
| Fourth Round | Stan Wawrinka | Win | 6-1, 6-4 |
| Quarterfinals | Taylor Fritz | Win | 6-4, 4-6, 6-4 |
| Semifinals | Carlos Alcaraz | Loss | 6-7 (4-7), 3-6 |
| Open 13 Provence | ||
| Surface: Hard | Date: Feb. 20 - Feb. 26 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Arthur Fils | Loss | Retired |
| ABN Amro World Tennis Tournament | ||
| Surface: Hard | Date: Feb. 13 - Feb. 19 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Benjamin Bonzi | Win | 6-2, 3-6, 6-1 |
| Second Round | Stefanos Tsitsipas | Win | 6-4, 6-3 |
| Quarterfinals | Stan Wawrinka | Win | 6-1, 6-3 |
| Semifinals | Tallon Griekspoor | Win | 7-5, 7-6 (7-5) |
| Final | Daniil Medvedev | Loss | 7-5, 2-6, 2-6 |
| Open Sud de France | ||
| Surface: Hard | Date: Feb. 6 - Feb. 12 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Marton Fucsovics | Win | |
| Quarterfinals | Lorenzo Sonego | Win | |
| Semifinals | Arthur Fils | Win | |
| Final | Maxime Cressy | Win |
| Australian Open | ||
| Surface: Hard | Date: Jan. 15 - Jan. 29 | Seed: 15 |
| Round | Opponent | W / L | Result |
| First Round | Kyle Edmund | Win | |
| Second Round | Tomas Martin Etcheverry | Win | |
| Third Round | Marton Fucsovics | Win | |
| Fourth Round | Stefanos Tsitsipas | Loss |
| Adelaide International 1 | ||
| Surface: Hard | Date: Jan. 1 - Jan. 8 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Kyle Edmund | Win | |
| Second Round | Thanasi Kokkinakis | Win | |
| Quarterfinals | Sebastian Korda | Loss |
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