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MLB Leaders |
| Rank | Name | Team | GP | GS | W | L | S | IP | H | R | ER | BB | K | Hld | BS | WHIP | ERA |
| 1 | Y. Darvish | Tex | 10 | 10 | 7 | 2 | 0 | 66.2 | 42 | 21 | 21 | 22 | 91 | 0 | 0 | 0.96 | 2.84 |
| 2 | A. Burnett | Pit | 11 | 11 | 3 | 5 | 0 | 70.0 | 49 | 21 | 20 | 25 | 85 | 0 | 0 | 1.06 | 2.57 |
| 3 | A. Sanchez | Det | 10 | 10 | 5 | 4 | 0 | 64.1 | 55 | 20 | 17 | 17 | 80 | 0 | 0 | 1.12 | 2.38 |
| 4 | J. Masterson | Cle | 11 | 11 | 7 | 3 | 0 | 76.0 | 59 | 27 | 27 | 27 | 76 | 0 | 0 | 1.13 | 3.20 |
| 5 | M. Scherzer | Det | 9 | 9 | 6 | 0 | 0 | 62.1 | 44 | 26 | 25 | 13 | 75 | 0 | 0 | 0.91 | 3.61 |
| 6 | M. Harvey | NYM | 10 | 10 | 5 | 0 | 0 | 70.0 | 41 | 15 | 15 | 17 | 74 | 0 | 0 | 0.83 | 1.93 |
| 7 | C. Buchholz | Bos | 10 | 10 | 7 | 0 | 0 | 72.2 | 49 | 14 | 14 | 27 | 73 | 0 | 0 | 1.05 | 1.73 |
| 8t | C. Kershaw | LAD | 10 | 10 | 5 | 2 | 0 | 73.1 | 42 | 14 | 11 | 18 | 72 | 0 | 0 | 0.82 | 1.35 |
| 8t | J. Samardzija | ChC | 10 | 10 | 2 | 6 | 0 | 63.2 | 50 | 27 | 23 | 22 | 72 | 0 | 0 | 1.13 | 3.25 |
| 8t | F. Hernandez | Sea | 10 | 10 | 5 | 3 | 0 | 69.2 | 58 | 19 | 16 | 12 | 72 | 0 | 0 | 1.00 | 2.07 |
| 11t | J. Verlander | Det | 10 | 10 | 5 | 4 | 0 | 59.0 | 60 | 26 | 24 | 21 | 69 | 0 | 0 | 1.37 | 3.66 |
| 11t | A. Wainwright | StL | 10 | 10 | 6 | 3 | 0 | 72.0 | 64 | 21 | 19 | 6 | 69 | 0 | 0 | 0.97 | 2.38 |
| 11t | J. Shields | KC | 10 | 10 | 2 | 5 | 0 | 73.0 | 55 | 21 | 20 | 15 | 69 | 0 | 0 | 0.96 | 2.47 |
| 14 | R. Dempster | Bos | 10 | 10 | 2 | 5 | 0 | 55.2 | 49 | 33 | 29 | 29 | 67 | 0 | 0 | 1.40 | 4.69 |
| 15 | L. Lynn | StL | 10 | 10 | 7 | 1 | 0 | 61.0 | 43 | 20 | 20 | 24 | 66 | 0 | 0 | 1.10 | 2.95 |
| 16 | T. Lincecum | SF | 10 | 10 | 3 | 4 | 0 | 60.2 | 58 | 34 | 32 | 27 | 64 | 0 | 0 | 1.40 | 4.75 |
| 17 | M. Bumgarner | SF | 10 | 10 | 4 | 2 | 0 | 65.1 | 49 | 23 | 21 | 17 | 63 | 0 | 0 | 1.01 | 2.89 |
| 18t | S. Strasburg | Was | 10 | 10 | 2 | 5 | 0 | 64.1 | 51 | 28 | 19 | 21 | 62 | 0 | 0 | 1.12 | 2.66 |
| 18t | S. Miller | StL | 9 | 9 | 5 | 3 | 0 | 57.0 | 38 | 13 | 11 | 15 | 62 | 0 | 0 | 0.93 | 1.74 |
| 20t | C. Sale | CWS | 9 | 9 | 5 | 2 | 0 | 64.0 | 44 | 19 | 18 | 15 | 61 | 0 | 0 | 0.92 | 2.53 |
| 20t | H. Iwakuma | Sea | 10 | 10 | 5 | 1 | 0 | 64.2 | 45 | 19 | 17 | 11 | 61 | 0 | 0 | 0.87 | 2.37 |
| 22t | C. Wilson | LAA | 10 | 10 | 4 | 3 | 0 | 63.2 | 59 | 30 | 24 | 32 | 60 | 0 | 0 | 1.43 | 3.39 |
| 22t | H. Ryu | LAD | 10 | 10 | 5 | 2 | 0 | 62.2 | 57 | 25 | 23 | 22 | 60 | 0 | 0 | 1.26 | 3.30 |
| 24 | J. Peavy | CWS | 8 | 8 | 5 | 2 | 0 | 51.2 | 42 | 20 | 19 | 13 | 58 | 0 | 0 | 1.06 | 3.31 |
| 25t | C. Hamels | Phi | 10 | 10 | 1 | 7 | 0 | 62.2 | 56 | 31 | 31 | 24 | 57 | 0 | 0 | 1.28 | 4.45 |
| 25t | G. Gonzalez | Was | 10 | 10 | 3 | 2 | 0 | 59.0 | 43 | 25 | 24 | 26 | 57 | 0 | 0 | 1.17 | 3.66 |