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MLB Leaders |
| Rank | Name | Team | GP | GS | W | L | S | IP | H | R | ER | BB | K | Hld | BS | WHIP | ERA |
| 1t | Y. Darvish | Tex | 9 | 9 | 7 | 1 | 0 | 60.2 | 37 | 20 | 20 | 19 | 86 | 0 | 0 | 0.92 | 2.97 |
| 1t | M. Moore | TB | 8 | 8 | 7 | 0 | 0 | 48.0 | 29 | 13 | 13 | 25 | 51 | 0 | 0 | 1.13 | 2.44 |
| 3t | C. Buchholz | Bos | 9 | 9 | 6 | 0 | 0 | 65.2 | 44 | 13 | 13 | 24 | 69 | 0 | 0 | 1.04 | 1.78 |
| 3t | H. Kuroda | NYY | 9 | 9 | 6 | 2 | 0 | 58.2 | 42 | 13 | 13 | 14 | 39 | 0 | 0 | 0.95 | 1.99 |
| 3t | J. Lester | Bos | 9 | 9 | 6 | 0 | 0 | 59.2 | 45 | 19 | 18 | 15 | 50 | 0 | 0 | 1.01 | 2.72 |
| 3t | J. Masterson | Cle | 9 | 9 | 6 | 2 | 0 | 63.0 | 50 | 22 | 22 | 24 | 60 | 0 | 0 | 1.17 | 3.14 |
| 7t | D. Fister | Det | 8 | 8 | 5 | 1 | 0 | 50.0 | 51 | 22 | 17 | 8 | 40 | 0 | 0 | 1.18 | 3.06 |
| 7t | J. Guthrie | KC | 8 | 8 | 5 | 1 | 0 | 54.1 | 53 | 18 | 17 | 17 | 30 | 0 | 0 | 1.29 | 2.82 |
| 7t | J. Hammel | Bal | 9 | 9 | 5 | 2 | 0 | 50.1 | 59 | 35 | 32 | 20 | 36 | 0 | 0 | 1.57 | 5.72 |
| 7t | F. Hernandez | Sea | 9 | 9 | 5 | 2 | 0 | 64.2 | 50 | 13 | 11 | 10 | 64 | 0 | 0 | 0.93 | 1.53 |
| 7t | H. Iwakuma | Sea | 9 | 9 | 5 | 1 | 0 | 58.2 | 38 | 14 | 12 | 8 | 55 | 0 | 0 | 0.78 | 1.84 |
| 7t | J. Peavy | CWS | 7 | 7 | 5 | 1 | 0 | 45.2 | 38 | 16 | 15 | 8 | 51 | 0 | 0 | 1.01 | 2.96 |
| 7t | C. Sale | CWS | 9 | 9 | 5 | 2 | 0 | 64.0 | 44 | 19 | 18 | 15 | 61 | 0 | 0 | 0.92 | 2.53 |
| 7t | M. Scherzer | Det | 8 | 8 | 5 | 0 | 0 | 54.1 | 42 | 25 | 24 | 12 | 68 | 0 | 0 | 0.99 | 3.98 |
| 15t | A. Cobb | TB | 8 | 8 | 4 | 2 | 0 | 53.0 | 50 | 18 | 17 | 12 | 52 | 0 | 0 | 1.17 | 2.89 |
| 15t | K. Correia | Min | 8 | 8 | 4 | 3 | 0 | 53.2 | 58 | 20 | 20 | 8 | 22 | 0 | 0 | 1.23 | 3.35 |
| 15t | A. Griffin | Oak | 8 | 8 | 4 | 3 | 0 | 51.2 | 47 | 23 | 20 | 13 | 39 | 0 | 0 | 1.16 | 3.48 |
| 15t | T. Milone | Oak | 9 | 9 | 4 | 5 | 0 | 57.0 | 56 | 26 | 22 | 12 | 49 | 0 | 0 | 1.19 | 3.47 |
| 15t | B. Norris | Hou | 9 | 9 | 4 | 4 | 0 | 50.0 | 59 | 29 | 24 | 18 | 33 | 0 | 0 | 1.54 | 4.32 |
| 15t | A. Ogando | Tex | 9 | 9 | 4 | 2 | 0 | 49.2 | 43 | 19 | 17 | 19 | 37 | 0 | 0 | 1.25 | 3.08 |
| 15t | A. Pettitte | NYY | 8 | 8 | 4 | 3 | 0 | 49.1 | 49 | 23 | 21 | 15 | 39 | 0 | 0 | 1.30 | 3.83 |
| 15t | C. Sabathia | NYY | 9 | 9 | 4 | 3 | 0 | 59.1 | 61 | 24 | 21 | 15 | 54 | 0 | 0 | 1.28 | 3.19 |
| 15t | A. Sanchez | Det | 9 | 9 | 4 | 4 | 0 | 55.1 | 54 | 20 | 17 | 14 | 68 | 0 | 0 | 1.23 | 2.77 |
| 15t | J. Verlander | Det | 9 | 9 | 4 | 4 | 0 | 54.0 | 50 | 21 | 19 | 20 | 60 | 0 | 0 | 1.30 | 3.17 |