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MLB Leaders |
| Rank | Name | Team | GP | GS | W | L | S | IP | H | R | ER | BB | K | Hld | BS | WHIP | ERA |
| 1 | J. Shields | KC | 9 | 9 | 2 | 4 | 0 | 66.0 | 48 | 19 | 18 | 15 | 62 | 0 | 0 | 0.95 | 2.45 |
| 2 | C. Buchholz | Bos | 9 | 9 | 6 | 0 | 0 | 65.2 | 44 | 13 | 13 | 24 | 69 | 0 | 0 | 1.04 | 1.78 |
| 3t | F. Hernandez | Sea | 9 | 9 | 5 | 2 | 0 | 64.2 | 50 | 13 | 11 | 10 | 64 | 0 | 0 | 0.93 | 1.53 |
| 3t | A. Wainwright | StL | 9 | 9 | 5 | 3 | 0 | 64.2 | 60 | 20 | 18 | 5 | 63 | 0 | 0 | 1.01 | 2.51 |
| 5 | C. Kershaw | LAD | 9 | 9 | 4 | 2 | 0 | 64.1 | 39 | 13 | 10 | 17 | 67 | 0 | 0 | 0.87 | 1.40 |
| 6 | C. Sale | CWS | 9 | 9 | 5 | 2 | 0 | 64.0 | 44 | 19 | 18 | 15 | 61 | 0 | 0 | 0.92 | 2.53 |
| 7t | M. Harvey | NYM | 9 | 9 | 5 | 0 | 0 | 63.2 | 32 | 11 | 11 | 14 | 68 | 0 | 0 | 0.72 | 1.55 |
| 7t | C. Lee | Phi | 9 | 9 | 4 | 2 | 0 | 63.2 | 58 | 22 | 20 | 11 | 50 | 0 | 0 | 1.08 | 2.83 |
| 9 | J. Masterson | Cle | 9 | 9 | 6 | 2 | 0 | 63.0 | 50 | 22 | 22 | 24 | 60 | 0 | 0 | 1.17 | 3.14 |
| 10 | Y. Darvish | Tex | 9 | 9 | 7 | 1 | 0 | 60.2 | 37 | 20 | 20 | 19 | 86 | 0 | 0 | 0.92 | 2.97 |
| 11 | J. Lester | Bos | 9 | 9 | 6 | 0 | 0 | 59.2 | 45 | 19 | 18 | 15 | 50 | 0 | 0 | 1.01 | 2.72 |
| 12 | C. Sabathia | NYY | 9 | 9 | 4 | 3 | 0 | 59.1 | 61 | 24 | 21 | 15 | 54 | 0 | 0 | 1.28 | 3.19 |
| 13t | M. Latos | Cin | 9 | 9 | 4 | 0 | 0 | 58.2 | 54 | 23 | 19 | 15 | 51 | 0 | 0 | 1.18 | 2.91 |
| 13t | J. Zimmermann | Was | 8 | 8 | 7 | 1 | 0 | 58.2 | 42 | 11 | 11 | 9 | 39 | 0 | 0 | 0.87 | 1.69 |
| 13t | H. Kuroda | NYY | 9 | 9 | 6 | 2 | 0 | 58.2 | 42 | 13 | 13 | 14 | 39 | 0 | 0 | 0.95 | 1.99 |
| 13t | H. Iwakuma | Sea | 9 | 9 | 5 | 1 | 0 | 58.2 | 38 | 14 | 12 | 8 | 55 | 0 | 0 | 0.78 | 1.84 |
| 17 | M. Bumgarner | SF | 9 | 9 | 4 | 2 | 0 | 58.1 | 45 | 22 | 20 | 15 | 58 | 0 | 0 | 1.03 | 3.09 |
| 18 | T. Cahill | Ari | 9 | 9 | 3 | 4 | 0 | 58.0 | 44 | 17 | 16 | 24 | 43 | 0 | 0 | 1.17 | 2.48 |
| 19 | S. Strasburg | Was | 9 | 9 | 2 | 5 | 0 | 57.1 | 46 | 27 | 18 | 18 | 55 | 0 | 0 | 1.12 | 2.83 |
| 20t | J. Samardzija | ChC | 9 | 9 | 2 | 5 | 0 | 56.2 | 47 | 26 | 22 | 21 | 64 | 0 | 0 | 1.20 | 3.49 |
| 20t | C. Hamels | Phi | 9 | 9 | 1 | 6 | 0 | 56.2 | 49 | 29 | 29 | 24 | 47 | 0 | 0 | 1.29 | 4.61 |
| 22 | M. Cain | SF | 9 | 9 | 3 | 2 | 0 | 56.1 | 51 | 35 | 34 | 17 | 49 | 0 | 0 | 1.21 | 5.43 |
| 23 | A. Burnett | Pit | 9 | 9 | 3 | 4 | 0 | 56.0 | 41 | 18 | 17 | 19 | 72 | 0 | 0 | 1.07 | 2.73 |
| 24t | C. Wilson | LAA | 9 | 9 | 3 | 3 | 0 | 55.2 | 53 | 29 | 23 | 30 | 50 | 0 | 0 | 1.49 | 3.72 |
| 24t | J. Hellickson | TB | 9 | 9 | 2 | 2 | 0 | 55.2 | 55 | 36 | 36 | 17 | 46 | 0 | 0 | 1.29 | 5.82 |