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MLB Leaders |
| Rank | Name | Team | GP | GS | W | L | S | IP | H | R | ER | BB | K | Hld | BS | WHIP | ERA |
| 1 | C. Buchholz | Bos | 12 | 12 | 9 | 0 | 0 | 84.1 | 57 | 16 | 16 | 29 | 81 | 0 | 0 | 1.02 | 1.71 |
| 2 | C. Kershaw | LAD | 15 | 15 | 5 | 4 | 0 | 107.1 | 73 | 26 | 22 | 31 | 104 | 0 | 0 | 0.97 | 1.84 |
| 3 | H. Iwakuma | Sea | 15 | 15 | 7 | 2 | 0 | 100.1 | 72 | 26 | 23 | 17 | 90 | 0 | 0 | 0.89 | 2.06 |
| 4 | S. Miller | StL | 14 | 14 | 8 | 4 | 0 | 86.1 | 64 | 22 | 20 | 19 | 96 | 0 | 0 | 0.96 | 2.08 |
| 5 | M. Harvey | NYM | 15 | 15 | 6 | 1 | 0 | 104.0 | 71 | 25 | 25 | 23 | 115 | 0 | 0 | 0.90 | 2.16 |
| 6 | J. Locke | Pit | 14 | 14 | 6 | 1 | 0 | 82.1 | 58 | 21 | 20 | 36 | 60 | 0 | 0 | 1.14 | 2.19 |
| 7 | P. Corbin | Ari | 14 | 14 | 9 | 0 | 0 | 94.2 | 73 | 25 | 24 | 23 | 74 | 0 | 0 | 1.01 | 2.28 |
| 8 | F. Hernandez | Sea | 15 | 15 | 8 | 4 | 0 | 104.2 | 88 | 30 | 27 | 20 | 110 | 0 | 0 | 1.03 | 2.32 |
| 9 | A. Wainwright | StL | 15 | 15 | 10 | 4 | 0 | 110.0 | 102 | 31 | 29 | 9 | 100 | 0 | 0 | 1.01 | 2.37 |
| 10 | C. Sale | CWS | 12 | 12 | 5 | 5 | 0 | 85.1 | 58 | 26 | 23 | 19 | 86 | 0 | 0 | 0.90 | 2.43 |
| 11 | J. Zimmermann | Was | 14 | 14 | 9 | 3 | 0 | 99.2 | 79 | 30 | 27 | 14 | 67 | 0 | 0 | 0.93 | 2.44 |
| 12 | S. Strasburg | Was | 13 | 13 | 3 | 6 | 0 | 79.1 | 59 | 31 | 22 | 25 | 77 | 0 | 0 | 1.06 | 2.50 |
| 13 | C. Lee | Phi | 15 | 15 | 9 | 2 | 0 | 110.1 | 88 | 34 | 31 | 17 | 98 | 0 | 0 | 0.95 | 2.53 |
| 14 | E. Santana | KC | 14 | 14 | 5 | 5 | 0 | 99.0 | 82 | 32 | 29 | 15 | 77 | 0 | 0 | 0.98 | 2.64 |
| 15 | M. Leake | Cin | 14 | 14 | 7 | 3 | 0 | 88.2 | 89 | 28 | 26 | 19 | 62 | 0 | 0 | 1.22 | 2.64 |
| 16 | M. Minor | Atl | 14 | 14 | 8 | 2 | 0 | 90.2 | 70 | 31 | 27 | 18 | 85 | 0 | 0 | 0.97 | 2.68 |
| 17 | J. Shields | KC | 15 | 15 | 2 | 6 | 0 | 106.0 | 89 | 33 | 32 | 30 | 95 | 0 | 0 | 1.12 | 2.72 |
| 18 | T. Wood | ChC | 14 | 14 | 5 | 6 | 0 | 92.0 | 64 | 30 | 28 | 28 | 64 | 0 | 0 | 1.00 | 2.74 |
| 19 | A. Sanchez | Det | 13 | 13 | 6 | 5 | 0 | 81.2 | 71 | 28 | 25 | 23 | 101 | 0 | 0 | 1.15 | 2.76 |
| 20 | H. Kuroda | NYY | 14 | 14 | 6 | 5 | 0 | 87.1 | 72 | 27 | 27 | 19 | 60 | 0 | 0 | 1.04 | 2.78 |
| 21 | Y. Darvish | Tex | 15 | 15 | 7 | 3 | 0 | 101.1 | 67 | 34 | 32 | 31 | 137 | 0 | 0 | 0.97 | 2.84 |
| 22 | H. Ryu | LAD | 13 | 13 | 6 | 2 | 0 | 85.1 | 76 | 29 | 27 | 25 | 75 | 0 | 0 | 1.18 | 2.85 |
| 23 | B. Colon | Oak | 14 | 14 | 9 | 2 | 0 | 90.1 | 89 | 29 | 29 | 10 | 52 | 0 | 0 | 1.10 | 2.89 |
| 24 | A. Cobb | TB | 13 | 13 | 6 | 2 | 0 | 83.2 | 74 | 29 | 28 | 23 | 76 | 0 | 0 | 1.16 | 3.01 |
| 25 | S. Feldman | ChC | 13 | 13 | 6 | 5 | 0 | 79.2 | 67 | 34 | 27 | 21 | 60 | 0 | 0 | 1.10 | 3.05 |