Liga Santander
Transfers |
| Date | Player | Team From | Team To | Comments |
| 8/31/2021 | Matthew Hoppe | Schalke 04 | Mallorca | Transfer |
| Germany Bundesliga 2 | Liga Santander | Undisclosed | ||
| 8/31/2021 | Emerson | Barcelona | Tottenham Hotspur | Transfer |
| Liga Santander | English Premier League | Undisclosed | ||
| 8/31/2021 | Marc Cucurella | Getafe | Brighton & Hove Albion | Transfer |
| Liga Santander | English Premier League | Undisclosed | ||
| 8/31/2021 | Jonathan Silva | Leganés | Getafe | Transfer |
| Liga 1, 2, 3 | Liga Santander | Undisclosed | ||
| 8/31/2021 | E. Camavinga | Rennes | Real Madrid | Transfer |
| France Ligue 1 | Liga Santander | Undisclosed | ||
| 8/30/2021 | Dimitri Foulquier | Granada | València | Transfer |
| Liga Santander | Liga Santander | Undisclosed | ||
| 8/25/2021 | Matheus Cunha | Hertha BSC | Atlético Madrid | Transfer |
| Germany Bundesliga | Liga Santander | Undisclosed | ||
| 8/25/2021 | Thomas Delaney | Borussia Dortmund | Sevilla | Transfer |
| Germany Bundesliga | Liga Santander | Undisclosed | ||
| 8/25/2021 | Marcos Andre | Real Valladolid | València | Transfer |
| Liga 1, 2, 3 | Liga Santander | Undisclosed | ||
| 8/20/2021 | Rafa Mir | Wolverhampton Wanderers | Sevilla | Transfer |
| English Premier League | Liga Santander | Undisclosed | ||
| 8/20/2021 | Jakub Jankto | Sampdoria | Getafe | Transfer |
| Italy Serie A | Liga Santander | Undisclosed | ||
| 8/20/2021 | Martin Ödegaard | Real Madrid | Arsenal | Transfer |
| Liga Santander | English Premier League | Undisclosed | ||
| 8/20/2021 | Mamadou Sylla | Girona | Alavés | Transfer |
| Liga 1, 2, 3 | Liga Santander | Undisclosed | ||
| 8/19/2021 | Arnaut Danjuma | AFC Bournemouth | Villarreal | Transfer |
| England Championship | Liga Santander | Undisclosed | ||
| 8/19/2021 | Germán Pezzella | Fiorentina | Real Betis | Transfer |
| Italy Serie A | Liga Santander | Undisclosed | ||
| 8/17/2021 | Luís Maximiano | Sporting CP | Granada | Transfer |
| Portugal Liga | Liga Santander | Undisclosed | ||
| 8/15/2021 | Ludwig Augustinsson | Werder Bremen | Sevilla | Transfer |
| Germany Bundesliga 2 | Liga Santander | Undisclosed | ||
| 8/14/2021 | Raphaël Varane | Real Madrid | Manchester United | Transfer |
| Liga Santander | English Premier League | Undisclosed | ||
| 8/13/2021 | Gonzalo Montiel | River Plate | Sevilla | Transfer |
| Argentina Primera A | Liga Santander | Undisclosed | ||
| 8/9/2021 | Álvaro Alvaro Jimenez | Albacete | Cádiz | Transfer |
| Spain Liga Segunda B | Liga Santander | Undisclosed | ||
| 8/8/2021 | Johan Mojica | Girona | Elche | Transfer |
| Liga 1, 2, 3 | Liga Santander | Undisclosed | ||
| 6/11/2021 | Deyverson | Alavés | Palmeiras | Transfer |
| Liga Santander | Brazil Campeonato Paulista | |||
| 6/11/2021 | Deyverson | Alavés | Palmeiras | Transfer |
| Liga Santander | Brazil Serie A | |||
| 6/11/2021 | Asier Benito | Eibar | Asteras Tripolis | Transfer |
| Liga Santander | Greece Super League | |||
| 6/11/2021 | Juan Foyth | Villarreal | Villarreal | Transfer |
| Liga Santander | Liga Santander | |||
| 6/7/2021 | Gaizka Garitano | Eibar | Transfer | |
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