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NFL Weekly Leaders |
Top RB
| Rank | Player | Team | Yds | TD |
| 1 | Frank Gore | San Francisco 49ers | 110 | 1 |
| 2 | Ray Rice | Baltimore Ravens | 59 | 0 |
| 3 | Bernard Pierce | Baltimore Ravens | 33 | 0 |
| 4 | LaMichael James | San Francisco 49ers | 10 | 0 |
| 5 | Vonta Leach | Baltimore Ravens | 1 | 0 |
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