Transactions
| Date | Player | Pos | Transactions |
| 12/5 | Micah Abernathy | S | pract. squad add |
| 12/5 | Patrick Taylor | RB | pract. squad add |
| 12/3 | Micah Abernathy | S | active/prac. squad |
| 12/3 | Patrick Taylor | RB | active/prac. squad |
| 11/29 | Innis Gaines | S | active/prac. squad |
| 11/29 | Johnathan Abram | S | cut |
| 11/29 | Nick Guggemos | TE | pract. squad add |
| 11/28 | Innis Gaines | S | pract. squad add |
| 11/28 | Patrick Taylor | RB | pract. squad add |
| 11/26 | Innis Gaines | S | active/prac. squad |
| 11/26 | Patrick Taylor | RB | active/prac. squad |
| 11/25 | Patrick Taylor | RB | pract. squad add |
| 11/25 | Josh Babicz | TE | pract. squad del |
| 11/25 | Sean Rhyan | T | suspended 6 games (NFL Policy on PEDs) |
| 11/23 | Justin Hollins | LB | acquired from waiver |
| 11/23 | Patrick Taylor | RB | cut |
| 11/18 | La'Darius Hamilton | LB | pract. squad add |
| 11/17 | La'Darius Hamilton | LB | active/prac. squad |
| 11/15 | Kylin Hill | RB | cut |
| 11/15 | Amari Rodgers | WR | cut |
| 11/15 | Patrick Taylor | RB | active/prac. squad |
| 11/15 | Tim Ward | LB | pract. squad add |
| 11/15 | Dede Westbrook | WR | pract. squad add |
| 11/14 | Ramiz Ahmed | K | pract. squad add |
| 11/14 | La'Darius Hamilton | LB | pract. squad add |
| 11/12 | Corey Ballentine | CB | active/prac. squad |
| 11/12 | Ramiz Ahmed | K | active/prac. squad |
| 11/12 | La'Darius Hamilton | LB | active/prac. squad |
| 11/12 | Eric Stokes | CB | on IR ankle, knee |
| 11/9 | Jeff Cotton Jr. | WR | pract. squad add |
| 11/9 | Johnathan Abram | S | acquired from waiver |
| 11/9 | Rashan Gary | LB | on IR torn ACL |
| 11/8 | Kawaan Baker | WR | pract. squad del |
| 11/3 | Patrick Taylor | RB | pract. squad add |
| 11/2 | Kylin Hill | RB | Activated from PUPL |
| 11/1 | Patrick Taylor | RB | cut |
| 11/1 | Kobe Jones | LB | pract. squad del |
| 10/31 | Innis Gaines | S | pract. squad add |
| 10/31 | Kobe Jones | LB | pract. squad add |
| 10/29 | Innis Gaines | S | active/prac. squad |
| 10/29 | Kobe Jones | LB | active/prac. squad |
| 10/25 | Josh Babicz | TE | pract. squad add |
| 10/25 | Shaun Beyer | TE | pract. squad del |
| 10/24 | La'Darius Hamilton | LB | pract. squad add |
| 10/22 | La'Darius Hamilton | LB | active/prac. squad |
| 10/22 | Jake Hanson | C | on IR biceps |
| 10/19 | Kawaan Baker | WR | pract. squad add |
| 10/18 | Innis Gaines | S | pract. squad add |
| 10/18 | Benjie Franklin | CB | pract. squad del |
| 10/18 | Ray Wilborn | LB | pract. squad del |
| 10/17 | Juwann Winfree | WR | pract. squad add |
| 10/17 | Luke Tenuta | T | acquired from waiver |
| 10/15 | Juwann Winfree | WR | active/prac. squad |
| 10/15 | Tipa Galeai | LB | on IR hamstring |
| 10/4 | Eric Wilson | LB | active/prac. squad |
| 10/3 | Kiondre Thomas | CB | pract. squad add |
| 10/1 | Caleb Jones | T | reserve/non football injury |
| 10/1 | Kiondre Thomas | CB | active/prac. squad |
| 9/28 | Corey Ballentine | CB | pract. squad add |
| 9/26 | Juwann Winfree | WR | pract. squad add |
| 9/24 | Patrick Taylor | RB | active/prac. squad |
| 9/24 | Juwann Winfree | WR | active/prac. squad |
| 9/22 | Travis Fulgham | WR | pract. squad add |
| 9/22 | Mike Brown | S | pract. squad del |
| 9/20 | DQ Thomas | LB | pract. squad add |
| 9/20 | Travis Fulgham | WR | pract. squad del |
| 9/20 | Gabe Brkic | K | cut |
| 9/20 | Gabe Brkic | K | off IR undisclosed |
| 9/19 | Patrick Taylor | RB | pract. squad add |
| 9/17 | Patrick Taylor | RB | active/prac. squad |
| 9/15 | Malik Taylor | WR | cut |
| 9/15 | Malik Taylor | WR | off IR shoulder |
| 9/14 | Mike Brown | S | pract. squad add |
| 9/13 | Caleb Jones | T | active/prac. squad |
| 9/12 | Micah Abernathy | S | pract. squad add |
| 9/12 | Juwann Winfree | WR | pract. squad add |
| 9/10 | Micah Abernathy | S | active/prac. squad |
| 9/10 | Juwann Winfree | WR | active/prac. squad |
| 9/9 | Akial Byers | DT | cut |
| 9/9 | Innis Gaines | S | cut |
| 9/9 | Akial Byers | DT | off IR undisclosed |
| 9/9 | Innis Gaines | S | off IR undisclosed |
| 9/8 | Shawn Davis | S | cut |
| 9/8 | Shawn Davis | S | off IR undisclosed |
| 9/7 | Ishmael Hyman | WR | cut |
| 9/7 | Ishmael Hyman | WR | off IR undisclosed |
| 9/5 | Ramiz Ahmed | K | pract. squad add |
| 9/2 | Micah Abernathy | S | pract. squad add |
| 9/2 | Rico Gafford | CB | pract. squad del |
| 9/2 | Nate Becker | TE | cut |
| 9/2 | Alize Mack | TE | cut |
| 9/2 | Nate Becker | TE | off IR undisclosed |
| 9/2 | Alize Mack | TE | off IR undisclosed |
| 9/1 | Shaun Beyer | TE | pract. squad add |
| 9/1 | Benjie Franklin | CB | pract. squad add |
| 9/1 | Juwann Winfree | WR | pract. squad add |
| 9/1 | Danny Davis | WR | cut |
| 9/1 | Danny Davis | WR | off IR undisclosed |
| 8/31 | Rudy Ford | S | signed |
| 8/31 | Micah Abernathy | S | cut |
| 8/31 | Danny Etling | QB | pract. squad add |
| 8/31 | Travis Fulgham | WR | pract. squad add |
| 8/31 | Rico Gafford | CB | pract. squad add |
| 8/31 | Tyler Goodson | RB | pract. squad add |
| 8/31 | La'Darius Hamilton | LB | pract. squad add |
| 8/31 | Jack Heflin | DT | pract. squad add |
| 8/31 | Caleb Jones | T | pract. squad add |
| 8/31 | Kobe Jones | LB | pract. squad add |
| 8/31 | Chris Slayton | DT | pract. squad add |
| 8/31 | Patrick Taylor | RB | pract. squad add |
| 8/31 | Kiondre Thomas | CB | pract. squad add |
| 8/31 | Ray Wilborn | LB | pract. squad add |
| 8/31 | Nate Becker | TE | on IR undisclosed |
| 8/31 | Akial Byers | DT | on IR undisclosed |
| 8/31 | Shawn Davis | S | on IR undisclosed |
| 8/31 | Innis Gaines | S | on IR undisclosed |
| 8/31 | Ishmael Hyman | WR | on IR undisclosed |
| 8/31 | Alize Mack | TE | on IR undisclosed |
| 8/30 | Morgan Burnett | S | signed One-day contract |
| 8/30 | Danny Etling | QB | cut |
| 8/30 | Jack Heflin | DT | cut |
| 8/30 | Kiondre Thomas | CB | cut |
| 8/30 | Sal Cannella | TE | cut |
| 8/30 | Juwann Winfree | WR | cut |
| 8/30 | Morgan Burnett | S | retired |
| 8/30 | Caleb Jones | T | cut |
| 8/30 | Ramiz Ahmed | K | cut |
| 8/30 | De'Vante Cross | S | cut |
| 8/30 | Kabion Ento | CB | cut |
| 8/30 | Dexter Williams | RB | cut |
| 8/30 | Chris Slayton | DT | cut |
| 8/30 | Tyler Goodson | RB | cut |
| 8/30 | Rico Gafford | CB | cut |
| 8/30 | La'Darius Hamilton | LB | cut |
| 8/30 | Michal Menet | C | cut |
| 8/30 | Patrick Taylor | RB | cut |
| 8/30 | Travis Fulgham | WR | cut |
| 8/30 | Kobe Jones | LB | cut |
| 8/30 | Ray Wilborn | LB | cut |
| 8/28 | Ty Summers | LB | cut |
| 8/24 | Cole Schneider | C | cut |
| 8/24 | Donte Vaughn | CB | cut |
| 8/24 | Cole Schneider | C | off IR undisclosed |
| 8/24 | Donte Vaughn | CB | off IR undisclosed |
| 8/24 | Vernon Scott | S | on IR shoulder |
| 8/24 | Danny Davis | WR | on IR undisclosed |
| 8/23 | Kylin Hill | RB | Placed on PUPL right knee |
| 8/22 | Dominique Dafney | TE | cut |
| 8/22 | Dominique Dafney | TE | off IR undisclosed |
| 8/21 | Ty Clary | C | cut |
| 8/21 | Chauncey Manac | LB | cut |
| 8/18 | Malik Taylor | WR | on IR shoulder |
| 8/17 | De'Vante Cross | S | signed |
| 8/17 | Travis Fulgham | WR | acquired from waiver |
| 8/17 | Dominique Dafney | TE | on IR undisclosed |
| 8/16 | B.J. Baylor | RB | cut |
| 8/16 | George Moore | T | cut |
| 8/16 | Ellis Brooks | LB | cut |
| 8/16 | Cole Schneider | C | on IR undisclosed |
| 8/16 | Donte Vaughn | CB | on IR undisclosed |
| 8/15 | Randy Ramsey | LB | cut |
| 8/15 | Nate Becker | TE | acquired from waiver |
| 8/15 | Gabe Brkic | K | on IR undisclosed |
| 8/14 | Ramiz Ahmed | K | signed |
| 8/10 | Dexter Williams | RB | signed/unrest FA |
| 8/10 | Steve Wirtel | C | cut |
| 8/10 | Osirus Mitchell | WR | cut |
| 8/10 | Micah Abernathy | S | signed |
| 7/28 | Ishmael Hyman | WR | signed |
| 7/27 | Caliph Brice | LB | cut |
| 7/26 | Ty Clary | C | signed |
| 7/26 | Osirus Mitchell | WR | signed |
| 7/26 | Donte Vaughn | CB | signed |
| 7/26 | Hauati Pututau | DT | cut |
| 7/26 | Tre Sterling | S | cut |
| 7/26 | Raleigh Texada | CB | cut |
| 7/25 | Dallin Leavitt | S | signed |
| 7/22 | Eli Wolf | TE | cut |
| 7/21 | Sal Cannella | TE | signed |
| 7/20 | Christian Watson | WR | signed/draft choice Four-year contract (through 2025) |
| 6/17 | Kurt Benkert | QB | cut |
| 6/13 | Allen Lazard | WR | re-signed/rest FA One-year contract (through 2022) |
| 6/13 | Gabe Brkic | K | acquired from waiver |
| 6/13 | Dominik Eberle | K | cut |
| 5/26 | Romeo Doubs | WR | signed/draft choice Four-year contract (through 2025) |
| 5/26 | Zach Tom | C | signed/draft choice Four-year contract (through 2025) |
| 5/24 | Chris Slayton | DT | acquired from waiver |
| 5/20 | JJ Molson | K | cut |
| 5/18 | Jack Coco | TE | signed |
| 5/17 | Jahmir Johnson | T | cut |
| 5/16 | Jaire Alexander | CB | re-signed Four-year extension (through 2026) |
| 5/11 | Eli Wolf | TE | acquired from waiver |
| 5/11 | Chris Blair | WR | cut |
| 5/9 | Rasheed Walker | T | signed/draft choice Four-year contract (through 2025) |
| 5/9 | Kobe Jones | LB | signed |
| 5/6 | Quay Walker | LB | signed/draft choice Four-year contract (fifth-year option) |
| 5/6 | Devonte Wyatt | DT | signed/draft choice Four-year contract (fifth-year option) |
| 5/6 | Sean Rhyan | T | signed/draft choice Four-year contract (through 2025) |
| 5/6 | Kingsley Enagbare | LB | signed/draft choice Four-year contract (through 2025) |
| 5/6 | Tariq Carpenter | S | signed/draft choice Four-year contract (through 2025) |
| 5/6 | Jonathan Ford | DT | signed/draft choice Four-year contract (through 2025) |
| 5/6 | Samori Toure | WR | signed/draft choice Four-year contract (through 2025) |
| 5/2 | Caliph Brice | LB | signed |
| 5/2 | B.J. Baylor | RB | signed |
| 5/2 | Ellis Brooks | LB | signed |
| 5/2 | Akial Byers | DT | signed |
| 5/2 | Danny Davis | WR | signed |
| 5/2 | Tyler Goodson | RB | signed |
| 5/2 | Jahmir Johnson | T | signed |
| 5/2 | Caleb Jones | T | signed |
| 5/2 | Chauncey Manac | LB | signed |
| 5/2 | George Moore | T | signed |
| 5/2 | Hauati Pututau | DT | signed |
| 5/2 | Cole Schneider | C | signed |
| 5/2 | Tre Sterling | S | signed |
| 5/2 | Raleigh Texada | CB | signed |
| 4/29 | Darnell Savage | S | team exercises option Fifth-year option on rookie contract |
| 4/29 | Rashan Gary | LB | team exercises option Fifth-year option on rookie contract |
| 4/18 | Krys Barnes | LB | re-signed/excl. FA One-year contract (through 2022) |
| 4/18 | Dominique Dafney | TE | re-signed/excl. FA One-year contract (through 2022) |
| 4/18 | Jake Hanson | C | re-signed/excl. FA One-year contract (through 2022) |
| 4/18 | Yosh Nijman | T | re-signed/excl. FA One-year contract (through 2022) |
| 4/18 | Randy Ramsey | LB | re-signed/excl. FA One-year contract (through 2022) |
| 4/18 | Malik Taylor | WR | re-signed/excl. FA One-year contract (through 2022) |
| 4/14 | Sammy Watkins | WR | signed/unrest FA One-year contract (through 2022) |
| 4/6 | Whitney Mercilus | LB | retired |
| 3/26 | Keisean Nixon | CB | signed/unrest FA One-year contract (through 2022) |
| 3/22 | Jarran Reed | DT | signed/unrest FA One-year contract (through 2022) |
| 3/21 | Robert Tonyan | TE | re-signed/unrest FA One-year contract (through 2022) |
| 3/20 | Rasul Douglas | CB | re-signed/unrest FA Three-year contract (through 2024) |
| 3/17 | Pat O'Donnell | P | signed/unrest FA Two-year contract (through 2023) |
| 3/16 | Lucas Patrick | G | Declared Free Agent |
| 3/16 | Corey Bojorquez | P | Declared Free Agent |
| 3/16 | Oren Burks | LB | Declared Free Agent |
| 3/16 | Rasul Douglas | CB | Declared Free Agent |
| 3/16 | Dennis Kelly | T | Declared Free Agent |
| 3/16 | Kevin King | CB | Declared Free Agent |
| 3/16 | Tyler Lancaster | DT | Declared Free Agent |
| 3/16 | Whitney Mercilus | LB | Declared Free Agent |
| 3/16 | Equanimeous St. Brown | WR | Declared Free Agent |
| 3/16 | Chandon Sullivan | CB | Declared Free Agent |
| 3/16 | Robert Tonyan | TE | Declared Free Agent |
| 3/16 | Marquez Valdes-Scantling | WR | Declared Free Agent |
| 3/16 | Allen Lazard | WR | Restricted Free Agent |
| 3/16 | Henry Black | S | Declared Free Agent |
| 3/16 | Chauncey Rivers | LB | Declared Free Agent |
| 3/14 | Preston Smith | LB | re-signed Four-year extention (through 2026) |
| 3/14 | Za'Darius Smith | LB | cut |
| 3/14 | Billy Turner | G | cut |
| 3/14 | De'Vondre Campbell | LB | re-signed Five-year contract (through 2026) |
| 3/8 | Aaron Rodgers | QB | re-signed Four-year contract (through 2025) |
| 3/8 | Davante Adams | WR | Designated franchise player non-exclusive franchise tag |
| 2/22 | Dominik Eberle | K | signed |
Last updated Dec. 6, 5:49 P.M. ET
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