Injuries
| Date | Player | Status |
| 1/8 | R. Anderson | back (Out) |
| 1/8 | J. Conner | knee, shin (Out) |
| 1/8 | A. Hamilton Sr. | hip (Out) |
| 1/8 | C. McCoy | concussion (Out) |
| 1/8 | L. Fotu | shoulder (Questionable) |
| 1/8 | J. Jackson | hamstring (Questionable) |
| 1/8 | M. Wilson | neck (Questionable) |
| 1/6 | C. Banjo | concussion (IR) |
| 1/6 | J. Ledbetter | knee (IR) |
| 1/1 | J. Woods | biceps (Questionable) |
| 1/1 | K. Beachum | knee, ankle (Questionable) |
| 1/1 | A. Hamilton Sr. | hip (Out) |
| 1/1 | M. Wilson | neck (Questionable) |
| 1/1 | C. McCoy | concussion (Out) |
| 1/1 | T. Vallejo | knee (Questionable) |
| 1/1 | D. Hopkins | knee (Out) |
| 12/28 | B. Baker | shoulder fracture (IR) |
| 12/26 | A. Brewer | pectoral (IR) |
| 12/25 | K. Beachum | knee, ankle (Questionable) |
| 12/25 | A. Hamilton Sr. | back (Questionable) |
| 12/25 | C. McCoy | concussion (Out) |
| 12/25 | M. Garcia | shoulder (Questionable) |
| 12/25 | C. Washington | chest (Questionable) |
| 12/25 | M. Brown | groin (Questionable) |
| 12/18 | R. Coward | chest (Questionable) |
| 12/18 | C. Washington | chest (Questionable) |
| 12/18 | M. Wilson | neck (Questionable) |
| 12/18 | M. Brown | illness (Questionable) |
| 12/18 | A. Hamilton Sr. | back (Questionable) |
| 12/14 | R. Moore | groin (IR) |
| 12/14 | K. Murray | torn right ACL (IR) |
| 12/12 | R. Coward | chest (Out) |
| 12/12 | R. Moore | groin (Out) |
| 12/12 | C. Washington | chest (Questionable) |
| 11/27 | G. Dortch | thumb (Questionable) |
| 11/27 | R. Moore | groin (Out) |
| 11/27 | C. Washington | chest (Out) |
| 11/27 | T. McSorley | illness (Questionable) |
| 11/26 | Z. Ertz | knee (IR) |
| 11/26 | D. Humphries | back (IR) |
| 11/21 | Z. Ertz | knee (Out) |
| 11/21 | D. Humphries | back (Out) |
| 11/21 | M. Garcia | shoulder (Questionable) |
| 11/21 | D. Hopkins | hamstring (Questionable) |
| 11/21 | K. Murray | hamstring (Questionable) |
| 11/13 | M. Garcia | shoulder (Out) |
| 11/13 | K. Murray | hamstring (Questionable) |
| 11/13 | D. Gardeck | ankle (Questionable) |
| 11/13 | D. Humphries | back (Questionable) |
| 11/13 | C. Matthew | hamstring (Questionable) |
| 11/13 | G. Dortch | groin (Questionable) |
| 11/13 | K. Barnes | concussion (Doubtful) |
| 11/13 | K. Strong | ankle (Questionable) |
| 11/12 | R. Hudson | knee (IR) |
| 11/9 | W. Hernandez | pectoral muscle (Injured-Reserve (DFR)) |
| 11/6 | K. Strong | ankle (Questionable) |
| 11/6 | M. Garcia | shoulder (Out) |
| 11/6 | R. Hudson | knee (Out) |
| 11/6 | B. Baker | ankle (Questionable) |
| 11/6 | D. Humphries | back (Questionable) |
| 11/6 | J. Ledbetter | ribs (Questionable) |
| 11/6 | C. Matthew | hamstring (Out) |
| 11/6 | J. Conner | ribs (Questionable) |
| 11/6 | D. Gardeck | ankle (Questionable) |
| 11/6 | A. Lee | illness (Questionable) |
| 11/2 | D. Williams | hip (IR) |
| 10/30 | J. Jackson | groin (Out) |
| 10/30 | M. Garcia | shoulder (Out) |
| 10/30 | D. Gardeck | ankle (Out) |
| 10/30 | R. Hudson | knee (Out) |
| 10/30 | D. Humphries | back (Questionable) |
| 10/30 | C. Matthew | hamstring (Out) |
| 10/30 | J. Conner | ribs (Out) |
| 10/30 | M. Prater | right hip (Questionable) |
| 10/30 | D. Williams | knee (Questionable) |
| 10/26 | R. Lawrence | right shoulder (IR) |
| 10/20 | M. Brown | foot (Injured-Reserve (DFR)) |
| 10/20 | J. Conner | ribs (Questionable) |
| 10/20 | D. Gardeck | ankle (Out) |
| 10/20 | R. Hudson | knee (Out) |
| 10/20 | M. Prater | right hip (Questionable) |
| 10/20 | J. Pugh | knee (IR) |
| 10/20 | J. Thompson | hamstring (Questionable) |
| 10/20 | D. Williams | knee (Out) |
| 10/16 | R. Fenton | hamstring (Out) |
| 10/16 | R. Anderson | illness (Questionable) |
| 10/16 | J. Conner | ribs (Out) |
| 10/16 | D. Williams | knee (Out) |
| 10/16 | M. Garcia | toe (Questionable) |
| 10/16 | R. Hudson | knee (Questionable) |
| 10/16 | R. Lawrence | hand (Questionable) |
| 10/8 | N. Vigil | hamstring (IR) |
| 10/2 | R. Hudson | knee (Questionable) |
| 10/2 | R. Lawrence | hand (Out) |
| 10/2 | Z. Turner | ankle (Out) |
| 10/2 | J. Watt | calf (Questionable) |
| 10/2 | A. Green | knee (Out) |
| 10/2 | Z. Collins | shoulder (Questionable) |
| 10/2 | R. Moore | hamstring (Questionable) |
| 10/2 | M. Prater | right hip (Questionable) |
| 10/2 | M. Brown | foot, not injury related (Questionable) |
| 9/25 | R. Moore | hamstring (Out) |
| 9/25 | Z. Turner | ankle (Out) |
| 9/25 | J. Conner | ankle (Questionable) |
| 9/18 | R. Moore | hamstring (Out) |
| 9/18 | J. Pugh | neck (Questionable) |
| 9/18 | J. Thompson | toe (Questionable) |
| 9/18 | J. Watt | calf (Questionable) |
| 9/13 | K. Barnes | high-ankle sprain (Injured-Reserve (DFR)) |
| 9/11 | J. Watt | calf (Questionable) |
| 9/11 | Z. Ertz | calf (Questionable) |
| 9/11 | J. Pugh | neck (Questionable) |
| 9/11 | R. Moore | hamstring (Out) |
| 9/7 | C. McCoy | calf (Injured-Reserve (DFR)) |
| 9/1 | C. Washington | chest (Injured-Reserve (DFR)) |
| 9/1 | A. Wesley | groin, hip (IR) |
| 9/1 | L. Collier | undisclosed (Injured-Reserve (DFR)) |
| 8/31 | T. Daley | undisclosed (IR) |
| 8/31 | G. Long | undisclosed (IR) |
| 8/31 | J. Miles | undisclosed (IR) |
| 8/31 | C. Pierce Jr. | undisclosed (IR) |
| 8/31 | E. Banks | undisclosed (IR) |
| 8/30 | M. Hayes | undisclosed (IR) |
| 8/17 | E. Fry | undisclosed (IR) |
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