Depth Chart
| Offense | |||
| Position | |||
| Left Tackle | Charles Leno Jr. | Badara Traore | |
| Left Guard | Cody Whitehair | Alex Bars | Arlington Hambright |
| Center | Sam Mustipher | ||
| Right Guard | Germain Ifedi | Lachavious Simmons | Dieter Eiselen |
| Right Tackle | Rashaad Coward | Jason Spriggs | |
| Wide Receiver | Allen Robinson II | Riley Ridley | DeAndre Carter |
| Wide Receiver | Darnell Mooney | Cordarrelle Patterson | Rodney Adams |
| Wide Receiver | Anthony Miller | Javon Wims | Thomas Ives |
| Running Back | David Montgomery | Cordarrelle Patterson | Ryan Nall |
| Tight End | Jimmy Graham | Cole Kmet | Demetrius Harris |
| Quarterback | Mitchell Trubisky | Nick Foles | |
| Defense | |||
| Position | |||
| Defensive End | Mario Edwards Jr. | Brent Urban | LaCale London |
| Nose Tackle | Bilal Nichols | John Jenkins | Daniel McCullers |
| Defensive Tackle | Akiem Hicks | ||
| Left Outside Linebacker | Khalil Mack | Trevis Gipson | James Vaughters |
| Left Inside Linebacker | Roquan Smith | Josh Woods | |
| Right Outside Linebacker | Robert Quinn | Barkevious Mingo | Ledarius Mack |
| Right Inside Linebacker | Danny Trevathan | Joel Iyiegbuniwe | |
| Left Cornerback | Jaylon Johnson | Buster Skrine | Kindle Vildor |
| Right Cornerback | Kyle Fuller | Duke Shelley | Teez Tabor |
| Strong Safety | Tashaun Gipson Sr. | Deon Bush | DeAndre Houston-Carson |
| Free Safety | Eddie Jackson | Sherrick McManis | Marqui Christian |
| Special Teams | |||
| Position | |||
| Kicker | Cairo Santos | ||
| Kick-Offs | Cairo Santos | ||
| Punter | Pat O'Donnell | ||
| Kick Returner | Cordarrelle Patterson | Darnell Mooney | Anthony Miller |
| Punt Returner | Anthony Miller | ||
| Holder | Pat O'Donnell | ||
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