Depth Chart
| Offense | |||
| Position | |||
| Left Tackle | Charles Leno Jr. | Jason Spriggs | |
| Left Guard | James Daniels | Corey Levin | |
| Center | Cody Whitehair | Sam Mustipher | Corey Levin |
| Right Guard | Rashaad Coward | Germain Ifedi | Corey Levin |
| Right Tackle | Bobby Massie | Alex Bars | |
| Wide Receiver | Allen Robinson II | Javon Wims | Alex Wesley |
| Wide Receiver | Cordarrelle Patterson | Thomas Ives | Darnell Mooney |
| Wide Receiver | Anthony Miller | Riley Ridley | Reggie Davis |
| Running Back | Tarik Cohen | David Montgomery | Ryan Nall |
| Tight End | Cole Kmet | Jimmy Graham | Demetrius Harris |
| Quarterback | Mitchell Trubisky | Nick Foles | |
| Defense | |||
| Position | |||
| Left Defensive End | Akiem Hicks | Roy Robertson-Harris | Brent Urban |
| Nose Tackle | Eddie Goldman | ||
| Right Defensive End | Bilal Nichols | Abdullah Anderson | Trevis Gipson |
| Left Outside Linebacker | Khalil Mack | Isaiah Irving | |
| Left Inside Linebacker | Danny Trevathan | Josh Woods | |
| Right Outside Linebacker | Robert Quinn | Devante Bond | |
| Right Inside Linebacker | Roquan Smith | ||
| Left Cornerback | Kyle Fuller | Buster Skrine | Duke Shelley |
| Right Cornerback | Artie Burns | Jaylon Johnson | Michael Joseph |
| Strong Safety | Deon Bush | Jordan Lucas | |
| Free Safety | Eddie Jackson | DeAndre Houston-Carson | |
| Special Teams | |||
| Position | |||
| Kicker | Eddy Pineiro | ||
| Kick-Offs | Eddy Pineiro | ||
| Punter | Pat O'Donnell | ||
| Kick Returner | Cordarrelle Patterson | Anthony Miller | |
| Punt Returner | Tarik Cohen | Eddie Jackson | Duke Shelley |
| Holder | Pat O'Donnell | ||
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