Transactions
| Date | Player | Pos | Transactions |
| 10/12 | Brian Johnson | K | active/prac. squad |
| 10/12 | Cody Parkey | K | cut |
| 10/12 | Brian Poole | CB | cut |
| 10/12 | Desmond Trufant | CB | cut |
| 10/12 | Christian Ringo | DE | signed |
| 10/12 | Derrick Kelly II | T | pract. squad del |
| 10/12 | Wynton McManis | LB | pract. squad del |
| 10/12 | Brian Poole | CB | off IR undisclosed |
| 10/11 | Jordan Mills | T | pract. squad add |
| 10/9 | Christian Ringo | DE | cut |
| 10/9 | Kenny Stills | WR | active/prac. squad |
| 10/9 | Jordan Mills | T | active/prac. squad |
| 10/6 | Cody Parkey | K | signed |
| 10/6 | Devine Ozigbo | RB | active/prac. squad |
| 10/6 | Ryquell Armstead | RB | pract. squad add |
| 10/6 | Tony Jones Jr. | RB | on IR right ankle sprain |
| 10/5 | Aldrick Rosas | K | cut |
| 10/5 | Jalyn Holmes | DE | active/prac. squad |
| 10/5 | Bryce Thompson | CB | pract. squad add |
| 10/4 | Jordan Mills | T | pract. squad add |
| 10/4 | Kenny Stills | WR | pract. squad add |
| 10/2 | Kenny Stills | WR | active/prac. squad |
| 10/2 | Jordan Mills | T | active/prac. squad |
| 9/28 | Jordan Mills | T | pract. squad add |
| 9/28 | Ka'dar Hollman | CB | pract. squad del |
| 9/27 | Austin Reiter | C | pract. squad add |
| 9/27 | Kenny Stills | WR | pract. squad add |
| 9/25 | Austin Reiter | C | active/prac. squad |
| 9/25 | Kenny Stills | WR | active/prac. squad |
| 9/25 | Michael Thomas | WR | reinstated |
| 9/22 | Wynton McManis | LB | pract. squad add |
| 9/22 | Jordan Miller | CB | pract. squad add |
| 9/20 | Jalyn Holmes | DE | pract. squad add |
| 9/20 | Austin Reiter | C | pract. squad add |
| 9/20 | Wynton McManis | LB | cut |
| 9/20 | Jordan Miller | CB | cut |
| 9/18 | Jalyn Holmes | DE | active/prac. squad |
| 9/18 | Austin Reiter | C | active/prac. squad |
| 9/18 | Wynton McManis | LB | active/prac. squad |
| 9/18 | Jordan Miller | CB | active/prac. squad |
| 9/18 | Chase Hansen | LB | on IR groin |
| 9/17 | Alex Armah | RB | active/prac. squad |
| 9/17 | Wynton McManis | LB | pract. squad add |
| 9/17 | Kwon Alexander | LB | on IR elbow |
| 9/17 | Marcus Davenport | DE | on IR shoulder |
| 9/16 | Adam Prentice | RB | pract. squad add |
| 9/15 | Aldrick Rosas | K | active/prac. squad |
| 9/15 | Jordan Miller | CB | pract. squad add |
| 9/15 | Austin Reiter | C | pract. squad add |
| 9/14 | Kenny Stills | WR | pract. squad add |
| 9/14 | Adam Prentice | RB | cut |
| 9/14 | Jeff Heath | S | active/prac. squad |
| 9/14 | Caleb Benenoch | G | pract. squad add |
| 9/14 | Michael Thomas | WR | reserve/non football injury COVID-19 |
| 9/14 | Jaleel Johnson | DT | pract. squad del |
| 9/13 | Jeff Heath | S | pract. squad add |
| 9/13 | Aldrick Rosas | K | pract. squad add |
| 9/13 | Montravius Adams Sr. | DT | signed |
| 9/13 | Jordan Miller | CB | cut |
| 9/13 | Bradley Roby | CB | suspension lifted |
| 9/11 | Montravius Adams Sr. | DT | cut |
| 9/11 | Jeff Heath | S | pract. squad add |
| 9/11 | Jeff Heath | S | active/prac. squad |
| 9/11 | Aldrick Rosas | K | active/prac. squad |
| 9/11 | Albert Huggins | DT | active/prac. squad |
| 9/11 | Jordan Miller | CB | active/prac. squad |
| 9/11 | Caleb Benenoch | G | pract. squad del |
| 9/10 | Jeff Heath | S | cut |
| 9/10 | Ken Crawley | CB | on IR hamstring |
| 9/10 | Tre'Quan Smith | WR | on IR hamstring |
| 9/8 | Bradley Roby | CB | traded for 2022 (3rd) and 2023 (6th) picks |
| 9/7 | Latavius Murray | RB | cut |
| 9/7 | Desmond Trufant | CB | signed |
| 9/6 | Bryan Mills | CB | pract. squad del |
| 9/6 | Chris Hogan | WR | signed |
| 9/6 | Trevor Siemian | QB | signed |
| 9/6 | Montravius Adams Sr. | DT | signed |
| 9/6 | Ka'dar Hollman | CB | pract. squad add |
| 9/6 | Jalyn Holmes | DE | pract. squad add |
| 9/6 | Jaleel Johnson | DT | pract. squad add |
| 9/6 | Derrick Kelly II | T | pract. squad add |
| 9/6 | Dylan Mabin | CB | pract. squad add |
| 9/6 | Jordan Miller | CB | pract. squad add |
| 9/6 | Aldrick Rosas | K | pract. squad add |
| 9/6 | Wynton McManis | LB | pract. squad del |
| 9/6 | Wil Lutz | K | on IR core muscle |
| 9/6 | Nick Vannett | TE | on IR right leg |
| 9/1 | Adam Prentice | RB | acquired from waiver |
| 9/1 | Bryce Thompson | CB | cut |
| 9/1 | Marcus Willoughby | LB | cut |
| 9/1 | Aldrick Rosas | K | cut |
| 9/1 | Alex Armah | RB | pract. squad add |
| 9/1 | Kawaan Baker | WR | pract. squad add |
| 9/1 | Caleb Benenoch | G | pract. squad add |
| 9/1 | Josiah Bronson | DT | pract. squad add |
| 9/1 | Albert Huggins | DT | pract. squad add |
| 9/1 | Wynton McManis | LB | pract. squad add |
| 9/1 | Bryan Mills | CB | pract. squad add |
| 9/1 | KeiVarae Russell | CB | pract. squad add |
| 9/1 | Kevin White | WR | pract. squad add |
| 9/1 | Easop Winston Jr. | WR | pract. squad add |
| 9/1 | Ethan Wolf | TE | pract. squad add |
| 9/1 | Marcus Willoughby | LB | off IR undisclosed |
| 9/1 | Bryce Thompson | CB | off IR undisclosed |
| 8/31 | Devonta Freeman | RB | cut |
| 8/31 | Alex Armah | RB | cut |
| 8/31 | Kawaan Baker | WR | cut |
| 8/31 | Easop Winston Jr. | WR | cut |
| 8/31 | Ethan Wolf | TE | cut |
| 8/31 | Josiah Bronson | DT | cut |
| 8/31 | Christian Montano | G | cut |
| 8/31 | Bryan Mills | CB | cut |
| 8/31 | Derrick Kelly II | T | cut |
| 8/31 | Eric Burrell | S | cut |
| 8/31 | Shaq Smith | LB | cut |
| 8/31 | Natrell Jamerson | CB | cut |
| 8/31 | R.J. McIntosh | DT | cut |
| 8/31 | J.R. Sweezy | G | cut |
| 8/31 | Caleb Benenoch | G | cut |
| 8/31 | Michael Thomas | WR | Placed on PUPL ankle surgery |
| 8/31 | Trevor Siemian | QB | cut |
| 8/31 | Chris Hogan | WR | cut |
| 8/31 | Jordan Mills | T | cut |
| 8/31 | KeiVarae Russell | CB | cut |
| 8/31 | Damion Square | DT | cut |
| 8/31 | Kevin White | WR | cut |
| 8/31 | Grant Haley | CB | cut |
| 8/31 | Albert Huggins | DT | cut |
| 8/31 | Wynton McManis | LB | cut |
| 8/31 | Deuce Wallace | CB | cut |
| 8/27 | Damion Square | DT | signed |
| 8/27 | Sutton Smith | LB | cut |
| 8/27 | Bryce Thompson | CB | on IR undisclosed |
| 8/26 | KeiVarae Russell | CB | reinstated |
| 8/25 | Kyle Murphy | T | cut |
| 8/25 | Kyle Murphy | T | off IR undisclosed |
| 8/25 | Marcus Willoughby | LB | on IR undisclosed |
| 8/24 | Nolan Cooney | P | cut |
| 8/24 | Jalen Dalton | DT | on IR torn triceps |
| 8/24 | Brian Poole | CB | on IR undisclosed |
| 8/24 | Ethan Greenidge | T | on IR undisclosed |
| 8/22 | Tommylee Lewis | WR | cut |
| 8/22 | Tommylee Lewis | WR | off IR undisclosed |
| 8/21 | Adonis Alexander | CB | cut |
| 8/21 | Brett Maher | K | cut |
| 8/21 | Jalen McCleskey | WR | cut |
| 8/21 | Quentin Poling | LB | cut |
| 8/21 | Jalen McCleskey | WR | off IR hamstring |
| 8/21 | Quentin Poling | LB | off IR undisclosed |
| 8/21 | Brett Maher | K | off IR undisclosed |
| 8/21 | Adonis Alexander | CB | off IR undisclosed |
| 8/21 | Tommylee Lewis | WR | on IR undisclosed |
| 8/20 | Josh Pederson | TE | cut |
| 8/20 | Aldrick Rosas | K | signed |
| 8/20 | Jeff Heath | S | signed |
| 8/20 | Michael Brown | G | cut |
| 8/20 | Michael Brown | G | off IR undisclosed |
| 8/19 | Adonis Alexander | CB | on IR undisclosed |
| 8/19 | Michael Brown | G | on IR undisclosed |
| 8/18 | Bryan Mills | CB | signed |
| 8/18 | Natrell Jamerson | CB | signed |
| 8/18 | Kevin White | WR | signed |
| 8/18 | Jordan Mills | T | signed |
| 8/18 | Caleb Benenoch | G | signed |
| 8/18 | Jake Lampman | WR | cut |
| 8/18 | Lawrence Woods | CB | cut |
| 8/17 | Brett Maher | K | on IR undisclosed |
| 8/16 | Stevie Scott III | RB | cut |
| 8/16 | Prince Amukamara | CB | cut |
| 8/16 | Noah Spence | DE | cut |
| 8/16 | KeiVarae Russell | CB | reserve/non football injury COVID-19 |
| 8/16 | Kyle Murphy | T | on IR undisclosed |
| 8/13 | Keith Washington II | CB | cut |
| 8/13 | Lawrence Woods | CB | signed |
| 8/13 | Keith Washington II | CB | off IR wrist |
| 8/13 | Quentin Poling | LB | on IR undisclosed |
| 8/12 | R.J. McIntosh | DT | acquired from waiver |
| 8/12 | Jalen McCleskey | WR | on IR hamstring |
| 8/10 | Patrick Robinson | CB | retired |
| 8/10 | Brett Maher | K | signed |
| 8/7 | Josh Pederson | TE | signed |
| 8/7 | Ryan Glasgow | DT | retired |
| 8/5 | Kendall Donnerson | DE | cut |
| 8/4 | Kwon Alexander | LB | signed One-year contract (through 2021) |
| 8/4 | Adonis Alexander | CB | signed |
| 8/4 | Keith Washington II | CB | on IR wrist |
| 8/2 | Prince Amukamara | CB | signed |
| 8/2 | KeiVarae Russell | CB | signed |
| 8/2 | J.R. Sweezy | G | signed/unrest FA |
| 8/2 | Lorenzo Neal Jr. | DT | cut |
| 8/2 | Lawrence Woods | CB | cut |
| 8/2 | Dylan Soehner | TE | on IR undisclosed |
| 8/1 | Devonta Freeman | RB | signed |
| 7/30 | Tommylee Lewis | WR | signed |
| 7/27 | Kendall Donnerson | DE | signed |
| 7/27 | Brian Poole | CB | signed/unrest FA |
| 7/26 | Chris Hogan | WR | signed |
| 7/16 | David Onyemata | DT | suspended 6 games (NFL Policy on PEDs) |
| 6/30 | Ryan Ramczyk | T | re-signed Five-year extension (through 2025) |
| 6/11 | Drew Brees | QB | retired |
| 6/8 | Payton Turner | DE | signed/draft choice Four-year contract (fifth-year option) |
| 6/8 | Pete Werner | LB | signed/draft choice Four-year contract (through 2024) |
| 6/8 | Paulson Adebo | CB | signed/draft choice Four-year contract (through 2024) |
| 6/8 | Ian Book | QB | signed/draft choice Four-year contract (through 2024) |
| 6/8 | Landon Young | T | signed/draft choice Four-year contract (through 2024) |
| 6/8 | Kawaan Baker | WR | signed/draft choice Four-year contract (through 2024) |
| 5/19 | Eric Burrell | S | signed |
| 5/18 | Alex Hoffman | G | retired |
| 5/17 | Kyle Murphy | T | signed |
| 5/17 | Quentin Poling | LB | signed |
| 5/17 | Ken Crawley | CB | re-signed/unrest FA |
| 5/16 | Lorenzo Neal Jr. | DT | signed |
| 5/15 | Sutton Smith | LB | signed |
| 5/15 | Deuce Wallace | CB | signed |
| 5/15 | Easop Winston Jr. | WR | signed |
| 5/15 | Eric Burrell | S | cut |
| 5/15 | Trill Williams | S | cut |
| 5/12 | Stevie Scott III | RB | signed |
| 5/12 | Eric Burrell | S | signed |
| 5/11 | Trill Williams | S | signed |
| 5/10 | Josiah Bronson | DT | signed |
| 5/10 | Michael Brown | G | signed |
| 5/10 | Nolan Cooney | P | signed |
| 5/10 | Dylan Soehner | TE | signed |
| 5/6 | Albert Huggins | DT | signed |
| 5/2 | Bryce Thompson | CB | signed |
| 5/2 | Lawrence Woods | CB | signed |
| 5/2 | Shaq Smith | LB | signed |
| 5/2 | Alex Hoffman | G | signed |
| 4/29 | Marcus Davenport | DE | team exercises option Fifth-year option on rookie contract |
| 4/23 | Christian Montano | G | signed One-year contract (through 2021) |
| 4/20 | Will Clapp | C | re-signed/unrest FA One-year contract (through 2021) |
| 4/15 | Jalen McCleskey | WR | signed |
| 3/30 | Nick Vannett | TE | signed Three-year contract (through 2023) |
| 3/30 | Marcus Williams | S | re-signed/franchise One-year tender (through 2021) |
| 3/29 | P.J. Williams | CB | re-signed/unrest FA One-year contract (through 2021) |
| 3/29 | Tanoh Kpassagnon | DE | signed/unrest FA Two-year contract (through 2022) |
| 3/26 | Jameis Winston | QB | re-signed/unrest FA One-year contract (through 2021) |
| 3/19 | Alex Armah | RB | signed/unrest FA One-year contract (through 2021) |
| 3/19 | James Hurst | G | re-signed/unrest FA Three-year contract (through 2023) |
| 3/17 | James Hurst | G | Declared Free Agent |
| 3/17 | Jameis Winston | QB | Declared Free Agent |
| 3/17 | Will Clapp | C | Declared Free Agent |
| 3/17 | Alex Anzalone | LB | Declared Free Agent |
| 3/17 | Johnson Bademosi | CB | Declared Free Agent |
| 3/17 | Michael Burton | RB | Declared Free Agent |
| 3/17 | Ken Crawley | CB | Declared Free Agent |
| 3/17 | Bennie Fowler III | WR | Declared Free Agent |
| 3/17 | Justin Hardee Sr. | CB | Declared Free Agent |
| 3/17 | Trey Hendrickson | DE | Declared Free Agent |
| 3/17 | Sheldon Rankins | DT | Declared Free Agent |
| 3/17 | Craig Robertson | LB | Declared Free Agent |
| 3/17 | D.J. Swearinger | S | Declared Free Agent |
| 3/17 | P.J. Williams | CB | Declared Free Agent |
| 3/11 | Janoris Jenkins | CB | cut |
| 3/10 | Dwayne Washington | RB | re-signed One-year contract (through 2021) |
| 3/10 | Emmanuel Sanders | WR | cut |
| 3/10 | Kwon Alexander | LB | cut |
| 3/9 | Marcus Williams | S | Designated franchise player non-exclusive franchise tag |
| 3/6 | Ty Montgomery | WR | re-signed One-year contract (through 2021) |
| 3/4 | Thomas Morstead | P | cut |
| 3/3 | Jared Cook | TE | cut |
| 3/3 | Josh Hill | TE | cut |
Last updated Oct. 16, 1:10 A.M. ET
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