NFL Leaders |
Rushing Yards Gained
| Rank | Name | Team | G | Rushes | Rush Yds | Yd/G | Avg | TD |
| 1 | J. Jacobs | LV | 17 | 340 | 1653 | 97.2 | 4.86 | 12 |
| 2 | D. Henry | Ten | 16 | 349 | 1538 | 96.1 | 4.41 | 13 |
| 3 | N. Chubb | Cle | 17 | 302 | 1525 | 89.7 | 5.05 | 12 |
| 4 | S. Barkley | NYG | 16 | 295 | 1312 | 82.0 | 4.45 | 10 |
| 5 | M. Sanders | Phi | 17 | 259 | 1269 | 74.6 | 4.90 | 11 |
| 6 | D. Cook | Min | 17 | 264 | 1173 | 69.0 | 4.44 | 8 |
| 7 | J. Fields | Chi | 15 | 160 | 1143 | 76.2 | 7.14 | 8 |
| 8 | C. McCaffrey | SF | 17 | 244 | 1139 | 67.0 | 4.67 | 8 |
| 9 | T. Etienne Jr. | Jax | 17 | 220 | 1125 | 66.2 | 5.11 | 5 |
| 10 | A. Jones | GB | 17 | 213 | 1121 | 65.9 | 5.26 | 2 |
| 11 | J. Williams | Det | 17 | 262 | 1066 | 62.7 | 4.07 | 17 |
| 12 | K. Walker III | Sea | 15 | 228 | 1050 | 70.0 | 4.61 | 9 |
| 13 | R. Stevenson | NE | 17 | 210 | 1040 | 61.2 | 4.95 | 5 |
| 14 | N. Harris | Pit | 17 | 272 | 1034 | 60.8 | 3.80 | 7 |
| 15 | T. Allgeier | Atl | 16 | 210 | 1035 | 64.7 | 4.93 | 3 |
| 16 | T. Pollard | Dal | 16 | 193 | 1007 | 62.9 | 5.22 | 9 |
| 17 | D. Pierce | Hou | 13 | 220 | 939 | 72.2 | 4.27 | 4 |
| 18 | A. Ekeler | LAC | 17 | 204 | 915 | 53.8 | 4.49 | 13 |
| 19 | D. Foreman | Car | 17 | 203 | 914 | 53.8 | 4.50 | 5 |
| 20 | A. Kamara | NO | 15 | 223 | 897 | 59.8 | 4.02 | 2 |
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