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NFL Leaders |
Defensive Tackles
| Rank | Player | Team | G | TK | Sacks | Sack-Yds | Int | Fum | PD |
| 1 | J. Mayo | NE | 16 | 174 | 2.0 | 14.0 | 0 | 1 | 5 |
| 2 | S. Tulloch | Ten | 16 | 159 | 1.0 | 7.0 | 1 | 0 | 6 |
| 3 | P. Posluszny | Buf | 14 | 151 | 2.0 | 16.0 | 0 | 0 | 4 |
| 4 | C. Greenway | Min | 16 | 143 | 1.0 | 6.0 | 0 | 1 | 2 |
| 5 | R. Lewis | Bal | 16 | 139 | 2.0 | 8.0 | 2 | 2 | 4 |
| 6 | D. Whitner | Buf | 16 | 138 | 0.5 | 2.0 | 1 | 1 | 7 |
| 7 | L. Fletcher | Was | 16 | 136 | 2.5 | 20.5 | 1 | 3 | 11 |
| 8 | L. Timmons | Pit | 16 | 132 | 3.0 | 10.0 | 2 | 2 | 9 |
| 9 | P. Willis | SF | 15 | 128 | 6.0 | 46.0 | 0 | 2 | 5 |
| 10t | J. Anderson | Car | 16 | 126 | 3.5 | 25.5 | 1 | 2 | 5 |
| 10t | B. Urlacher | Chi | 16 | 126 | 4.0 | 20.5 | 1 | 2 | 10 |
| 12t | D. Jones | Cin | 16 | 125 | 1.0 | 9.0 | 0 | 1 | 2 |
| 12t | P. Lenon | Ari | 16 | 125 | 2.0 | 14.0 | 2 | 1 | 6 |
| 14 | D. Johnson | KC | 16 | 122 | 1.0 | 11.0 | 1 | 4 | 15 |
| 15 | J. Beason | Car | 16 | 121 | 1.0 | 7.0 | 1 | 2 | 8 |
| 16 | B. Ruud | TB | 16 | 120 | 2.0 | 8.0 | 1 | 2 | 4 |
| 17 | D. Williams | Den | 16 | 119 | 5.5 | 28.5 | 0 | 1 | 9 |
| 18t | B. James | Dal | 16 | 118 | 0.0 | 0.0 | 1 | 2 | 3 |
| 18t | C. Lofton | Atl | 16 | 118 | 2.0 | 16.0 | 1 | 3 | 3 |
| 20 | J. Laurinaitis | StL | 16 | 114 | 3.0 | 22.0 | 1 | 0 | 5 |
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