NFL Players |
| S | ||
| Name | Team | Pos |
| Rodger Saffold | Tennessee | G |
| Olive Sagapolu | Detroit | DT |
| Victor Salako | Buffalo | T |
| Christian Sam | Detroit | LB |
| Ty Sambrailo | Tennessee | T |
| Dru Samia | Minnesota | G |
| Drew Sample | Cincinnati | TE |
| Curtis Samuel | Carolina | WR |
| Deebo Samuel | San Francisco | WR |
| Jaylen Samuels | Pittsburgh | RB |
| Stanford Samuels III | Green Bay | CB |
| Rigoberto Sanchez | Indianapolis | P |
| Emmanuel Sanders | New Orleans | WR |
| Jason Sanders | Miami | K |
| Miles Sanders | Philadelphia | RB |
| Mohamed Sanu | New England | WR |
| Eric Saubert | Chicago | TE |
| Khalen Saunders | Kansas City | DT |
| Darnell Savage | Green Bay | S |
| Ira Savage-Lewis | Houston | DE |
| Marcus Sayles | Minnesota | CB |
| Patrick Scales | Chicago | TE |
| Bo Scarbrough | Detroit | RB |
| Charles Scarff | Baltimore | TE |
| Brennan Scarlett | Houston | LB |
| Cameron Scarlett | Tennessee | RB |
| Jordan Scarlett | Carolina | RB |
| Max Scharping | Houston | T |
| Matt Schaub | Atlanta | QB |
| Brandon Scherff | Washington | G |
| Austin Schlottmann | Denver | G |
| Spencer Schnell | Tampa Bay | WR |
| Joe Schobert | Jacksonville | LB |
| Dalton Schoen | Los Angeles | WR |
| Michael Schofield III | Carolina | G |
| Mason Schreck | Cincinnati | TE |
| Dalton Schultz | Dallas | TE |
| Mitchell Schwartz | Kansas City | T |
| Wes Schweitzer | Washington | G |
| Christian Scotland-Williamson | Pittsburgh | TE |
| Artavis Scott | Indianapolis | WR |
| Boston Scott | Philadelphia | RB |
| Da'Mari Scott | New York | WR |
| Delontae Scott | Green Bay | LB |
| Drew Scott | New York | C |
| Jaleel Scott | Baltimore | WR |
| JK Scott | Green Bay | P |
| Josiah Scott | Jacksonville | CB |
| Nick Scott | Los Angeles | S |
| Niles Scott | Buffalo | DT |
| Trent Scott | Los Angeles | T |
| Vernon Scott II | Green Bay | S |
| Ricky Seals-Jones | Kansas City | TE |
| Brad Seaton | Tampa Bay | T |
| Austin Seibert | Cleveland | K |
| Luke Sellers | Detroit | RB |
| Deadrin Senat | Atlanta | DT |
| Greg Senat | Kansas City | T |
| Andrew Sendejo | Cleveland | S |
| Coty Sensabaugh | Washington | CB |
| Tim Settle | Washington | DT |
| Isaac Seumalo | Philadelphia | G |
| Kamaal Seymour | Las Vegas | T |
| Zach Shackelford | Tampa Bay | C |
| Adam Shaheen | Miami | TE |
| David Sharpe | Las Vegas | T |
| Tajae Sharpe | Minnesota | WR |
| Tyler Shatley | Jacksonville | G |
| Josh Shaw | Arizona | CB |
| Kendall Sheffield | Atlanta | CB |
| Brady Sheldon | Cincinnati | LB |
| Brandon Shell | Seattle | T |
| Duke Shelley | Chicago | CB |
| Coleman Shelton | Los Angeles | C |
| Danny Shelton | Detroit | DT |
| Justice Shelton-Mosley | Kansas City | WR |
| Sojourn Shelton | Arizona | CB |
| Laviska Shenault Jr. | Jacksonville | WR |
| Sterling Shepard | New York | WR |
| Darrius Shepherd | Green Bay | WR |
| Nathan Shepherd | New York | DT |
| Trent Sherfield | Arizona | WR |
| Anthony Sherman | Kansas City | RB |
| Richard Sherman | San Francisco | CB |
| Kawann Short | Carolina | DT |
| Adam Shuler | Arizona | DE |
| Kyle Shurmur | Kansas City | QB |
| Trent Sieg | Las Vegas | C |
| Zach Sieler | Miami | DT |
| David Sills | New York | WR |
| Isaiah Simmons | Arizona | LB |
| Jeffery Simmons | Tennessee | DT |
| Jordan Simmons | Seattle | G |
| Justin Simmons | Denver | S |
| Lachavious Simmons | Chicago | G |
| Tyler Simmons | Houston | WR |
| Matt Simms | Atlanta | QB |
| John Simon | New England | DE |
| John Simpson | Las Vegas | G |
| Cam Sims | Washington | WR |
| LeShaun Sims | Cincinnati | CB |
| Steven Sims Jr. | Washington | WR |
| Devin Singletary | Buffalo | RB |
| Alex Singleton | Philadelphia | LB |
| Reid Sinnett | Tampa Bay | QB |
| Arryn Siposs | Detroit | P |
| Kemah Siverand | Seattle | CB |
| Deyon Sizer | Denver | DT |
| Dan Skipper | Detroit | T |
| Tuzar Skipper | Pittsburgh | LB |
| Buster Skrine | Chicago | CB |
| Justin Skule | San Francisco | T |
| Matt Skura | Baltimore | G |
| Chad Slade | New York | G |
| Matthew Slater | New England | WR |
| Darius Slay | Philadelphia | CB |
| Chris Slayton | New York | DT |
| Darius Slayton | New York | WR |
| Sam Sloman | Los Angeles | K |
| Connor Slomka | Jacksonville | RB |
| Joey Slye | Carolina | K |
| Wendell Smallwood | Pittsburgh | RB |
| Tanzel Smart | Los Angeles | DT |
| Aldon Smith | Dallas | LB |
| Alex Smith | Washington | QB |
| Andre Smith | Carolina | LB |
| Andre Smith | Baltimore | T |
| Braden Smith | Indianapolis | G |
| Cam Smith | Minnesota | LB |
| Chris Smith | Carolina | DE |
| Devin Smith | Dallas | WR |
| Donovan Smith | Tampa Bay | T |
| Emmanuel Smith | Kansas City | LB |
| Eric Smith | New York | T |
| Geno Smith | Seattle | QB |
| Harrison Smith | Minnesota | S |
| Irv Smith Jr. | Minnesota | TE |
| Ito Smith | Atlanta | RB |
| J'mar Smith | New England | QB |
| James Smith-Williams | Washington | DE |
| Jaylon Smith | Dallas | LB |
| Jeff Smith | New York | WR |
| Jimmy Smith | Baltimore | CB |
| Jonnu Smith | Tennessee | TE |
| Josh Smith | Tennessee | LB |
| JuJu Smith-Schuster | Pittsburgh | WR |
| Kaden Smith | New York | TE |
| Kahani Smith | Denver | S |
| Keith Smith | Atlanta | RB |
| Kobe Smith | Tennessee | NT |
| Lee Smith | Buffalo | TE |
| Maurice Smith | Washington | S |
| Preston Smith | Green Bay | LB |
| Prince Smith Jr. | New York | CB |
| Rashad Smith | Chicago | LB |
| Rod Smith | Las Vegas | RB |
| Rodney Smith | Carolina | RB |
| Roquan Smith | Chicago | LB |
| Ryan Smith | Tampa Bay | CB |
| Saivion Smith | Dallas | CB |
| Sean Smith | New York | P |
| Sutton Smith | Seattle | LB |
| T.J. Smith | Los Angeles | DT |
| Tre'Quan Smith | New Orleans | WR |
| Tremon Smith | Philadelphia | CB |
| Tye Smith | Tennessee | CB |
| Tyron Smith | Dallas | T |
| Vyncint Smith | New York | WR |
| Za'Darius Smith | Green Bay | LB |
| Fish Smithson | Baltimore | S |
| Dawuane Smoot | Jacksonville | DE |
| Durham Smythe | Miami | TE |
| Willie Snead IV | Baltimore | WR |
| L'Jarius Sneed | Kansas City | S |
| Benny Snell Jr. | Pittsburgh | RB |
| Matt Sokol | Detroit | TE |
| Nate Solder | New York | T |
| Daniel Sorensen | Kansas City | S |
| Andrew Soroh | Kansas City | CB |
| Shakir Soto | Seattle | DE |
| Quinton Spain | Buffalo | G |
| Breeland Speaks | Kansas City | DE |
| Marcel Spears Jr. | Cincinnati | LB |
| E.J. Speed | Indianapolis | LB |
| Noah Spence | New Orleans | DE |
| Diontae Spencer | Denver | WR |
| Robert Spillane | Pittsburgh | LB |
| Jason Spriggs | Chicago | T |
| Arrion Springs | Pittsburgh | CB |
| Jeremy Sprinkle | Washington | TE |
| Damion Square | Los Angeles | NT |
| Equanimeous St. Brown | Green Bay | WR |
| Tyree St. Louis | Los Angeles | T |
| Matthew Stafford | Detroit | QB |
| Taylor Stallworth | Indianapolis | DT |
| William Stanback | Las Vegas | RB |
| Donell Stanley | Miami | C |
| Jayson Stanley | Seattle | CB |
| Nate Stanley | Minnesota | QB |
| Ronnie Stanley | Baltimore | T |
| Johnny Stanton | Cleveland | RB |
| Dylan Stapleton | Houston | TE |
| Jordan Steckler | New Orleans | G |
| Terence Steele | Dallas | T |
| David Steinmetz | Houston | T |
| Logan Stenberg | Detroit | G |
| Simon Stepaniak | Green Bay | G |
| Shamar Stephen | Minnesota | DT |
| Linden Stephens | Seattle | CB |
| Bryce Sterk | Miami | TE |
| Jace Sternberger | Green Bay | TE |
| Tommy Stevens | New Orleans | QB |
| Darrell Stewart Jr. | Green Bay | WR |
| Grover Stewart | Indianapolis | DT |
| M.J. Stewart | Cleveland | CB |
| Orion Stewart | Tampa Bay | S |
| Easton Stick | Los Angeles | QB |
| Jarrett Stidham | New England | QB |
| Kenny Stills | Houston | WR |
| Aaron Stinnie | Tampa Bay | G |
| Geno Stone | Baltimore | S |
| Kentavius Street | San Francisco | DE |
| Chris Streveler | Arizona | QB |
| Justin Strnad | Denver | LB |
| Kevin Strong | Detroit | DT |
| Jason Strowbridge | Miami | DE |
| Xavier Su'a-Filo | Cincinnati | G |
| Nate Sudfeld | Philadelphia | QB |
| Ndamukong Suh | Tampa Bay | DT |
| Chandon Sullivan | Green Bay | CB |
| Stephen Sullivan | Seattle | WR |
| Ty Summers | Green Bay | LB |
| Rex Sunahara | Miami | LB |
| Nick Sundberg | Washington | C |
| Will Sunderland | Green Bay | CB |
| Keaton Sutherland | Miami | C |
| Cam Sutton | Carolina | TE |
| Cameron Sutton | Pittsburgh | CB |
| Courtland Sutton | Denver | WR |
| Freddie Swain | Seattle | WR |
| Isiah Swann | Cincinnati | CB |
| D.J. Swearinger | New Orleans | S |
| Josh Sweat | Philadelphia | DE |
| Montez Sweat | Washington | DE |
| Tommy Sweeney | Buffalo | TE |
| William Sweet | San Francisco | T |
| J.R. Sweezy | Arizona | G |
| D'Andre Swift | Detroit | RB |
| Ryan Switzer | Pittsburgh | WR |
| Tyrone Swoopes | Seattle | TE |
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