| Scoring Summary |
| First Quarter |
Buf | SF |
 |
FG |
7:25 |
David Akers 19 yd FG 7:25 Drive: 6 Plays, 79 Yards, 3:17 |
0 |
3 |
| Second Quarter |
Buf | SF |
 |
FG |
10:46 |
Rian Lindell 31 yd FG 10:46 Drive: 12 Plays, 75 Yards, 5:44 |
3 |
3 |
 |
TD |
9:54 |
Kyle Williams 43 yd pass from Alex Smith (David Akers kick) 9:54 Drive: 2 Plays, 74 Yards, 0:52 |
3 |
10 |
 |
TD |
0:24 |
Michael Crabtree 28 yd pass from Alex Smith (David Akers kick) 0:24 Drive: 1 Plays, 28 Yards, 0:05 |
3 |
17 |
| Third Quarter |
Buf | SF |
 |
TD |
9:06 |
Frank Gore 1 yd run (David Akers kick) 9:06 Drive: 5 Plays, 66 Yards, 2:44 |
3 |
24 |
| Fourth Quarter |
Buf | SF |
 |
TD |
14:12 |
Mario Manningham 10 yd pass from Alex Smith (David Akers kick) 14:12 Drive: 13 Plays, 94 Yards, 7:48 |
3 |
31 |
 |
TD |
9:55 |
Colin Kaepernick 16 yd run (David Akers kick) 9:55 Drive: 7 Plays, 67 Yards, 3:05 |
3 |
38 |
 |
TD |
1:11 |
Anthony Dixon 3 yd run (David Akers kick) 1:11 Drive: 11 Plays, 69 Yards, 6:29 |
3 |
45 |
| Team Stats |
| |
Buffalo |
San Francisco |
| First Downs |
10 |
29 |
| Rushing |
4 |
18 |
| Passing |
6 |
11 |
| Penalty |
0 |
0 |
| 3rd Down Efficiency |
2-10, 20% |
7-11, 64% |
| 4th down efficiency |
0-0, -% |
1-1, 100% |
| Red-Zone Efficiency |
0-1, 0% |
4-5, 80% |
| Goal-To-Go Efficiency |
0-0, -% |
2-3, 67% |
| Total Net Yards |
204 |
621 |
| Total Plays |
46 |
63 |
| Yards/Play |
4.4 |
9.9 |
| Net Rushing Yards |
89 |
311 |
| Rushes |
19 |
38 |
| Yards/Carry |
4.7 |
8.2 |
| Rushing TDs |
0 |
3 |
| Net Passing Yards |
115 |
310 |
| Comp-Att-Int |
16-26-1 |
19-25-0 |
| Yards/Attempt |
4.3 |
12.4 |
| Passing TDs |
0 |
3 |
| Sack-Yds |
1-11 |
0-0 |
| Return Yards |
115 |
68 |
| Punt Returns-Yards |
1-28 |
3-19 |
| Punt Return TDs |
0 |
0 |
| Kick Returns-Yards |
2-87 |
2-45 |
| Kick Return TDs |
0 |
0 |
| Int Returns-Yards |
0-0 |
1-4 |
| Int Return TDs |
0 |
0 |
| Punts-Average |
6-47.7 |
2-56.0 |
| Penalties - Yards |
5-30 |
7-53 |
| Fumbles Lost |
1-1 |
1-1 |
| Own-Recover-Yards |
0-0 |
0-0 |
| Own-Recover TDs |
0 |
0 |
| Opp-Recover-Yards |
1-0 |
1-5 |
| Opp-Recover TDs |
0 |
0 |
| Field Goals |
1-1, 100% |
1-1, 100% |
| Extra Points |
0-0, -% |
6-6, 100% |
| Two Point Conversions |
0-0, -% |
0-0, -% |
| Safeties |
0 |
0 |
| Time of Possession |
23:46 |
36:14 |
| Buffalo Passing |
| Player |
Cmp |
Att |
Comp % |
Yds |
TDs |
Int |
| R. Fitzpatrick |
16 |
26 |
61.5 |
126 |
0 |
1 |
| San Francisco Passing |
| Player |
Cmp |
Att |
Comp % |
Yds |
TDs |
Int |
| A. Smith |
18 |
24 |
75.0 |
303 |
3 |
0 |
| C. Kaepernick |
1 |
1 |
100.0 |
7 |
0 |
0 |
| Buffalo Kicking Statistics |
| Player |
FG |
Made |
Missed |
XP |
| R. Lindell |
1/1 |
31 |
- |
- |
| San Francisco Kicking Statistics |
| Player |
FG |
Made |
Missed |
XP |
| D. Akers |
1/1 |
19 |
- |
6/6 |
| Buffalo Interceptions |
| Player |
Int |
Yds |
| San Francisco Interceptions |
| Player |
Int |
Yds |
| C. Culliver |
1 |
4 |
| Buffalo Punt Returns |
| Player |
Ret |
Yds |
Avg |
| L. McKelvin |
1 |
28 |
28.0 |
| San Francisco Punt Returns |
| Player |
Ret |
Yds |
Avg |
| T. Ginn Jr. |
3 |
19 |
6.3 |
| San Francisco Kick Returns |
| Player |
Ret |
Yds |
Avg |
| K. Williams |
2 |
45 |
22.5 |
| Buffalo Punting |
| Player |
Punts |
Blocks |
Yds |
Avg |
in 20 |
| S. Powell |
6 |
0 |
286 |
47.7 |
2 |
| San Francisco Punting |
| Player |
Punts |
Blocks |
Yds |
Avg |
in 20 |
| A. Lee |
2 |
0 |
112 |
56.0 |
1 |
Officials: Jerome Boger (Referee), Tony Michalek (Umpire), Ed Camp (Head Linesman), Tom Stephan (Line Judge), Dyrol Prioleau (Field Judge), Joe Larrew (Side Judge), Tony Steratore (Back Judge)
Weather: 62°, Clear
Attendance: 69,732
Time of Game: 2:56

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